THE VISCERAL LESIONS PRODUCED IN MICE BY THE SALIVARY GLAND VIRUS OF MICE

THE VISCERAL LESIONS PRODUCED IN MICE BY THE SALIVARY GLAND VIRUS OF MICE
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小鼠唾液腺病毒对小鼠内脏损伤的研究

DOI:
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发表时间:
1936
影响因子:
15.3
通讯作者:
Margaret G. Smith
Margaret G. Smith
中科院分区:
医学1区
文献类型:
--
作者:
H. A. McCordock;Margaret G. Smith

文献摘要

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在小鼠体内和脑内接种同源唾液腺病毒,已经造成了含有核内包涵体的广泛内脏损害。皮下接种2周后,很少出现含有包涵体的小胰腺病变。许多经腹膜腔注射的动物在接种后第4天至第7天死亡。尽管肝脏和脾脏产生了广泛的病变,但病毒不能通过这些器官的乳剂传播。
Extensive visceral lesions containing intranuclear inclusions have been produced in mice by intraperitoneal and intracerebral inoculations of the homologous salivary gland virus. Rarely small pancreatic lesions containing inclusions have been encountered 2 weeks after subcutaneous inoculation. Many of the animals injected intraperitoneally died between the 4th and 7th day after inoculation. In spite of the extensive lesions produced in the liver and spleen, the virus could not be transferred with an emulsion of these organs.