Renal vascular transit time and tubular transit time dispersion for 99Tcm-MAG3
Renal vascular transit time and tubular transit time dispersion for 99Tcm-MAG3
复制标题
99Tcm-MAG3 的肾血管通过时间和肾小管通过时间离散度
DOI：
10.1097/00006231-199709000-00006
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发表时间：
1997
影响因子：
1.5
通讯作者：
E. Dubovsky
中科院分区：
文献类型：
--
作者：
C. Russell;M. Japanwalla;S. Khan;J. Scott;E. Dubovsky
正如 Taplin 所介绍的，肾脏转运时间通常是指肾小管转运时间，但也有人提出了其他肾脏转运的测量方法。在这里，我们检查了 30 名在动脉造影前进行基线和 ACE 抑制剂 99Tcm-MAG3 肾造影的患者的血管渡越时间（VTT，遵循 Rutland）和肾小管渡越时间的标准差（SDTT，遵循 Britton）。采用当天低剂量/高剂量方案进行肾造影；只有卡托普利后剂量足够高才能测量 VTT。卡托普利前，SDTT 的 Spearman 等级相关系数为 rho = 0.52（n = 53 个肾脏；P < 0.0002）；卡托普利后，rho = 0.54（n = 49 个肾脏；P < 0.0002）。对于 VTT，卡托普利后值为 rho = 0.24（n = 30 个肾脏；N.S.）。为了进行比较，对 Taplin 最初的传输时间测量计算了相同的统计数据：从注射到最大计数率的时间（峰值时间）。预卡托普利，峰值时间的 rho 为 0.47（n = 53 个肾脏；P < 0.001）；卡托普利后，rho 为 0.39（n = 50 个肾脏，P < 0.01）。这些发现证实了 SDTT 的诊断价值，但没有证实 VTT 的诊断价值。 SDTT 与动脉造影结果的相关性比峰值时间更好。
Renal transit time usually refers to tubular transit time, as introduced by Taplin, but other measures of renal transit have been proposed. Here we examine the vascular transit time (VTT, following Rutland) and the standard deviation of tubular transit time (SDTT, following Britton) in a group of 30 patients having baseline and ACE-inhibitor 99Tcm-MAG3 renography prior to arteriography. A same-day, low-dose/high-dose protocol was used for renography; only the post-captopril dose was high enough to measure VTT. Pre-captopril, the Spearman rank correlation coefficient for SDTT was rho = 0.52 (n = 53 kidneys; P < 0.0002); post-captopril, rho = 0.54 (n = 49 kidneys; P < 0.0002). For VTT, the post-captopril value was rho = 0.24 (n = 30 kidneys; N.S.). For comparison, the same statistics were calculated for Taplin's original measure of transit time: the time from injection to maximum count rate (peak time). Precaptopril, for peak time, rho was 0.47 (n = 53 kidneys; P < 0.001); post-captopril, rho was 0.39 (n = 50 kidneys, P < 0.01). These findings confirm the diagnostic value of SDTT but not of VTT. SDTT correlated better than peak time with the arteriographic findings.