Acute Gastroenteritis-Related Encephalopathy
Acute Gastroenteritis-Related Encephalopathy
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急性胃肠炎相关脑病
DOI：
10.1177/088307380101601208
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发表时间：
2001
影响因子：
1.9
通讯作者：
V. Wong
中科院分区：
文献类型：
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作者：
V. Wong
我们研究了1936例急性胃肠炎患儿的惊厥发生率。68名儿童发生惊厥（3.5%），分为三组：（1）细菌性（n = 13; 19%），（2）轮状病毒（n = 30，44%），（3）无微生物（n = 25; 37%）。只有第2组和第3组与脑病有显著相关性（P < .002）。估计相对风险以确定脑病的风险：轮状病毒与未分离出微生物（相对风险= 2.308），轮状病毒与细菌（相对风险= 1.846），细菌与未分离出微生物（相对风险= 1.25）。没有人出现癫痫。因此，急性胃肠炎相关脑病是一种良性疾病，在急性胃肠炎发作期间会出现单次或反复发作，预后良好。引起癫痫发作的潜在机制尚不清楚。我们应该确信，在急性胃肠炎发作期间反复发作无热性/热性惊厥的大多数儿童结局良好。（J Child Neurol 2001;16：906-910）。
We studied the incidence of convulsions in 1936 children with acute gastroenteritis. Sixty-eight children had convulsions (3.5%), which were categorized into three groups: (1) bacterial (n = 13; 19%), (2) Rotavirus (n = 30, 44%), and (3) no organism (n = 25; 37%). Only group 2 versus group 3 had a significant association with encephalopathy (P < .002). The relative risk was estimated to determine the risk of encephalopathy: Rotavirus versus no organism isolated (relative risk = 2.308), Rotavirus versus bacterial (relative risk = 1.846), and bacterial versus no organism (relative risk = 1.25). None developed epilepsy. Thus, acute gastroenteritis-related encephalopathy is a benign condition with single or recurrent seizures during an episode of acute gastroenteritis and an excellent prognosis. The underlying mechanism for provoking seizure is unknown. One should be reassured of a good outcome in the majority of children with recurrent episodes of afebrile/febrile seizures during an episode of acute gastroenteritis. (J Child Neurol 2001;16:906-910).