Long-Term Outcomes of Medication Intervention Using the Screening Tool of Older Persons Potentially Inappropriate Prescriptions Screening Tool to Alert Doctors to Right Treatment Criteria
Long-Term Outcomes of Medication Intervention Using the Screening Tool of Older Persons Potentially Inappropriate Prescriptions Screening Tool to Alert Doctors to Right Treatment Criteria
复制标题
DOI：
10.1111/jgs.14570
复制
发表时间：
2017-02-01
影响因子：
6.3
通讯作者：
Lerman, Yehuda
中科院分区：
文献类型：
--
作者：
Frankenthal, Dvora;Israeli, Avi;Lerman, Yehuda
目的：比较一项前瞻性随机对照试验(RCT)参与者24个月的结果，该试验基于老年人潜在不适当处方筛查工具(STOP)和筛查工具提醒医生正确治疗(START)(干预组)和被指派接受书面药物审查的患者(对照组)接受口头传达的建议的药物干预。设计：回溯性队列研究。设置：慢性护理老年病机构。部分：来自2012年4月至2013年9月期间进行的前瞻性RCT的359名参与者，测量：24个月随访的结果包括处方质量(根据STOP/START评估)、住院、跌倒、药物费用和全因死亡率。结果：潜在的不当处方(PIP)和潜在的处方遗漏(PPO)显著增加(P=.01)。
OBJECTIVES: To compare 24-month outcomes of participants of a prospective randomized controlled trial (RCT) assigned to undergo a medication intervention of orally communicated recommendations based on Screening Tool of Older Persons potentially inappropriate Prescriptions (STOPP) and Screening Tool to Alert Doctors to Right Treatment (START) (intervention group) with outcomes of those assigned to undergo written medication review (control group).DESIGN: Retrospective cohort study.SETTING: Chronic care geriatric facility.PARTICIPANTS: Of 359 participants from a prospective RCT conducted between April 2012 and September 2013, 306 were evaluable for another 12-month follow-up.MEASUREMENTS: Outcomes at 24-month follow-up included quality of prescribing (assessed according to STOPP/START), hospitalizations, falls, costs of medications, and all-cause mortality. Outcomes were compared with those reported at the beginning (baseline) and end (12-month follow-up) of the RCT.RESULTS: There was a significant rise in potentially inappropriate prescriptions (PIPs) (P =.01) and potentially prescriptions omissions (PPOs) (P