Dynamic intravenous coronary angiography using 2D monochromatic synchrotron radiation.
Dynamic intravenous coronary angiography using 2D monochromatic synchrotron radiation.
复制标题
使用二维单色同步辐射进行动态静脉冠状动脉造影。
DOI：
10.1259/bjr.72.853.10341685
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
M. Ando
中科院分区：
文献类型：
--
作者：
S. Ohtsuka;Y. Sugishita;T. Takeda;Y. Itai;J. Tada;K. Hyodo;M. Ando
一种比冠状动脉造影（CAG）侵入性更小、更容易的冠状动脉疾病检查方法已被寻求。我们开发了一种动态静脉冠状动脉造影（IVCAG）系统，使用同步辐射（SR），并已在临床上使用。4例疑似心绞痛患者行IVCAG检查。SR光束与硅晶体不对称反射，产生宽（150 mm x 80 mm）单色（37 keV） x射线束，其能量水平达到对造影剂的高灵敏度。静脉注射造影剂后，以33 ms间隔照射4 ms，以30张图像s-1进行动态IVCAG。用图像增强器获取图像，并用数字荧光系统记录图像。动态图像可以清晰地显示冠状动脉，并允许对冠状动脉解剖进行评估。2例患者无狭窄病变，1例患者右侧冠状动脉狭窄90%，其余患者左侧前降支（LAD）经皮腔内冠状动脉成形术部位狭窄25%。IVCAG的总照射剂量小于常规血管造影。动态IVCAG可以很容易地用于评估冠状动脉。
A method of examination for coronary artery disease that is less invasive and easier than coronary angiography (CAG) has been sought. We have developed a dynamic intravenous coronary angiography (IVCAG) system using synchrotron radiation (SR) and have used it clinically. Four patients suspected of having angina pectoris underwent IVCAG. An SR beam was reflected asymmetrically with a silicon crystal to produce a wide (150 mm x 80 mm) and monochromatic (37 keV) X-ray beam, with an energy level to achieve high sensitivity to the contrast agent. Following an intravenous injection of contrast agent, irradiation was applied for 4 ms periods at 33 ms intervals for dynamic IVCAG at 30 images s-1. Images were acquired with an image intensifier and recorded with a digital fluorography system. The dynamic images permitted clear visualization of the coronary arteries and permitted evaluation of coronary anatomy. Two patients exhibited no stenotic lesions, one patient had a 90% stenosis in the right coronary artery, and the remaining patient had a 25% stenosis at the site of previous percutaneous transluminal coronary angioplasty in the left anterior descending artery (LAD). The total irradiation doses used for IVCAG were less than those for conventional angiography. Dynamic IVCAG can be readily used for the evaluation of coronary arteries.