Studies on the blood supply of tumors in man. III. Vascular patterns of the liver by hepatic arteriography in vivo.

Studies on the blood supply of tumors in man. III. Vascular patterns of the liver by hepatic arteriography in vivo.
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人类肿瘤血液供应的研究。

DOI:
10.1093/jnci/12.1.107
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发表时间:
1951
期刊:
Journal of the National Cancer Institute
影响因子:
--
通讯作者:
Alice Grady
Alice Grady
中科院分区:
--
文献类型:
--
作者:
H. Bierman;R. Byron;Keith H. Kelley;Alice Grady

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被引文献

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Abnormal vascular patterns of the brain in the presence of tumors have been successfully visualized and applied to clinical practice by methods of cerebral angiography (1, 2). It has been demonstrated that neoplasms of other organs often exhibit an increased or abnormal arterial vascularity (3, 4). The visualization of the blood supply of various organs, therefore, could permit an additional means of discovering and localizing the presente of neoplasms.The study of neoplastic growths in the liver in man was aided by the work of Breedis and Young (5). By introducing contrasting dyes into the hepatic artery and the portal vein of livers of animals and human beings with primary and secondary neoplasms, it was shown that the blood suppiy of the neoplasms was derived almost exclusively from the hepatic artery. In contrast, 75 to 80 percent of the blood supply to the normal liver parenchyma is from the portal vein, and only 20 to 25 percent of the blood to the liver reaches it through the hepatic artery. These findings, on perfused livers obtained at autopsy, have been confirmed in this laboratory. 5