The projection from the superficial to the deep layers of the superior colliculus: an intracellular horseradish peroxidase injection study in the hamster
The projection from the superficial to the deep layers of the superior colliculus: an intracellular horseradish peroxidase injection study in the hamster
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上丘浅层到深层的投影：仓鼠细胞内辣根过氧化物酶注射研究
DOI：
10.1523/jneurosci.08-04-01384.1988
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发表时间：
1988
影响因子：
2
通讯作者：
R. Rhoades
中科院分区：
文献类型：
--
作者：
R. Mooney;Michael M. Nikoletseas;P. Hess;Z. Allen;A. Lewin;R. Rhoades
应用细胞内记录和辣根过氧化物酶（HRP）注射技术，观察了仓鼠上丘（SC）浅层[灰浅层（SGS）和视层（SO）上级神经元将轴突侧支传入该结构深层（SO腹侧）的投射。69个神经元进行了研究，从超过185个HRP填充的浅层细胞的样本的基础上，具有严重染色的轴突选择。在研究中包括的69个细胞中，43.4%（n = 30）将至少一个轴突侧支发送到深层。并不是所有的细胞类型在浅表层同样有助于这种层间投影：宽视野垂直细胞恢复率为78.6%（n = 11），窄视野垂直细胞恢复率为55.0%（n = 11），星状细胞恢复率为16.7%（n = 2），边缘细胞恢复率为40.0%（n = 2），18.2%（n = 2）的水平细胞和28.6%（n = 2）的神经元不能根据其投射到深层的体细胞形态进行分类。在给定的细胞类别中，具有深层轴突侧支的神经元和没有深层轴突侧支的神经元之间没有显著的形态学或生理学差异。大多数层间投射神经元的轴突深侧支仅限于中间灰质层（SGI）。在这一层中，轴突轴的最大部分位于与SC表面正交的投影线的侧面，该投影线穿过所讨论的细胞的索马。这些结果，沿着先前研究的结果（Mooney等人，1984），其证明深层细胞的树突可以延伸穿过SO并进入SGS，表明存在广泛的解剖学基底，通过该基底可以将感觉信息从浅层SC神经元传递到深层SC神经元。
Intracellular recording and horseradish peroxidase (HRP) injection techniques were employed to examine the projections of superficial layer [stratum griseum superficiale (SGS) and stratum opticum (SO)] superior collicular (SC) neurons in the hamster that sent axon collaterals into the deep laminae (those ventral to the SO) of this structure. Sixty-nine neurons were studied, selected from a sample of over 185 HRP-filled superficial layer cells on the basis of having heavily stained axons. Of the 69 cells included in the study, 43.4% (n = 30) sent at least one axon collateral to the deep laminae. Not all cell types in the superficial layers contributed equally to this interlaminar projection: 78.6% (n = 11) of the recovered wide-field vertical cells, 55.0% (n = 11) of the narrow-field vertical cells, 16.7% (n = 2) of the stellate cells, 40.0% (n = 2) of the marginal cells, 18.2% (n = 2) of the horizontal cells, and 28.6% (n = 2) of neurons we could not classify on the basis of their somadendritic morphology projected to the deep layers. Within a given cell class, there were no significant morphological or physiological differences between the neurons that possessed deep axon collaterals and those that did not. The deep axon collaterals of most of the interlaminar projection neurons were restricted to the stratum griseum intermediate (SGI). In this layer, the largest segment of the axon arbor was located lateral to a projection line that was orthogonal to the SC surface and that passed through the soma of the cell in question. These results, along with those of a previous study (Mooney et al., 1984), which demonstrated that the dendrites of deep layer cells may extend through the SO and into the SGS, indicate that there is an extensive anatomical substrate by which sensory information may be communicated from superficial to deep layer SC neurons.
视觉皮层损伤对兔上丘单个单位感受野特性的影响。
影响因子：
2.5
作者：
Graham,J;Berman,N;Murphy,EH
通讯作者：
Murphy,EH