Establishment of Gut Microbiome During Early Life and Its Relationship With Growth in Endangered Crested Ibis (Nipponia nippon).
Establishment of Gut Microbiome During Early Life and Its Relationship With Growth in Endangered Crested Ibis (Nipponia nippon).
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DOI：
10.3389/fmicb.2021.723682
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发表时间：
2021
影响因子：
5.2
通讯作者：
Tang K
中科院分区：
文献类型：
--
作者：
Zhu Y;Li Y;Yang H;He K;Tang K
脊椎动物生命早期的肠道微生物群可以影响宿主适合度。缺乏关于肠道微生物群如何在早期发育阶段使用频繁采样在鸟类肠道中定植以及微生物群多样性如何影响宿主生长的研究。在这里，我们研究了来自14个年轻的朱鹮（Nipponia nippon）的151个粪便样本的微生物组谱，这是一种濒危鸟类，在发育的早期阶段纵向收集了13个时间点，并研究了它们与宿主生长的相关性。肠道多样性在发育过程中表现出非线性变化，涉及多个定殖和灭绝事件，主要与变形菌门和厚壁菌门有关。随着年龄的增长，朱鹮幼鸟肠道菌群的相似性逐渐增加。此外，肠道微生物群表现出强大的时间结构和两个特定的发展阶段，后者的开始与引进新鲜泥鳅相吻合，梭杆菌和几个厚壁菌门的相对丰度有相当大的增加，这可能是参与脂质代谢。朱鹮雏鸡的生长速度与肠道微生物多样性呈负相关，与盐单胞菌科、链球菌、棒状杆菌科和迪茨氏菌科的丰度呈负相关。我们的研究结果强调了在脊椎动物发育的早期阶段研究微生物组发育时频繁采样的重要性。在鸟类发育的早期阶段，微生物多样性在宿主生长中的作用值得进一步研究。
Gut microbiota during early life could influence host fitness in vertebrates. Studies on how gut microbiota colonize the gut in birds using frequent sampling during early developmental stages and how shifts in microbiota diversity influence host growth are lacking. Here, we examine the microbiome profiles of 151 fecal samples from 14 young crested ibis (Nipponia nippon), an endangered bird species, collected longitudinally across 13 time points during the early stages of development and investigated their correlation with host growth. Gut diversity showed a non-linear change during development, which involved multiple colonization and extinction events, mainly associated with Proteobacteria and Firmicutes. Gut microbiota in young crested ibis became more similar with increasing age. In addition, gut microbiota exhibited a strong temporal structure and two specific developmental stages; the beginning of the latter stage coincided with the introduction of fresh loach, with a considerable increase in the relative abundance of Fusobacteria and several Firmicutes, which may be involved in lipid metabolism. Crested ibis chick growth rate was negatively correlated with gut microbiota diversity and negatively associated with the abundance of Halomonadaceae, Streptococci, Corynebacteriaceae, and Dietziaceae. Our findings highlight the importance of frequent sampling when studying microbiome development during early stages of development of vertebrates. The role of microbial diversity in host growth during the early stages of development of birds warrants further investigations.