A Study of Policies and Guidelines for Collecting, Processing, and Storing Coronavirus Disease 2019-Patient Biospecimens for Biobanking and Research
A Study of Policies and Guidelines for Collecting, Processing, and Storing Coronavirus Disease 2019-Patient Biospecimens for Biobanking and Research
复制标题
DOI：
10.1089/bio.2020.0099
复制
发表时间：
2020-12-04
影响因子：
1.6
通讯作者：
Shu, Zhiquan
中科院分区：
文献类型：
--
作者：
Gao, Frank, I;Tao, Liang;Shu, Zhiquan
生物库在开发新疫苗、药物、生物技术和治疗方法以预防和治疗各种人类疾病方面发挥着至关重要的作用。这使生物库处于应对全球持续爆发的严重流行病2019冠状病毒病（COVID-19）的最前沿。全球领先的公共卫生机构已为研究人员和生物库工作人员制定并建立了临时政策和指南，以安全和充分地处理COVID-19患者的传染性生物标本。本研究报告对这些重要的补充性政策和指导方针进行了研究。值得强调的是，COVID-19生物标本必须由配备正确个人防护装备的训练有素人员收集、处理和保存，以防止冠状病毒传播，并确保用于检测和研究的标本质量。本研究中包括的六个全球领先的公共卫生组织或机构是世界卫生组织、泛美卫生组织、美国疾病控制和预防中心、英国公共卫生局、美国食品和药物管理局以及加州大学旧金山弗朗西斯科的研究办公室。总之，遵循建议的指导和政策并采取极端预防措施对于确保收集的COVID-19生物标本的质量和所进行的研究或治疗的准确性以及防止任何可能的传播至关重要。低温生物学家和生物库工程师迫切需要努力优化COVID-19生物标本低温保存的方案，并开发用户友好且具有成本效益的设备，以满足标本生物库和运输的迫切和增加的需求。
Biobanking has been playing a crucial role in the development of new vaccines, drugs, biotechnology, and therapeutics for the prevention and treatment of a wide range of human diseases. This puts biobanks at the forefront of responding to the ongoing worldwide outbreak of the severe pandemic, coronavirus disease 2019 (COVID-19). The leading public health institutions around the world have developed and established interim policies and guidelines for researchers and biobank staff to handle the infectious biospecimens safely and adequately from COVID-19 patients. A study of these important and complementary policies and guidelines is conducted in this study. It should be emphasized that the COVID-19 biospecimens must be collected, processed, and preserved by trained personnel equipped with right personal protective equipment to prevent the transmission of the coronavirus and ensure the specimen quality for testing and research. Six of the leading global public health organizations or institutions included in this study are the World Health Organization, the Pan American Health Organization, the U.S. Centers for Disease Control and Prevention, the Public Health England, the U.S. Food and Drug Administration, and the Office of Research at the University of California, San Francisco. In conclusion, following the recommended guidance and policies with extreme precautions is essential to ensure the quality of the collected COVID-19 biospecimens and accuracy of the conducted research or treatment, and prevent any possible transmission. Efforts from cryobiologist and biobanking engineers to optimize the protocol of COVID-19 biospecimen cryopreservation and develop the user-friendly and cost-effective devices are urgently required to meet the urgent and increased needs in the specimen biobanking and transportation.