A novel putative G-protein-coupled receptor expressed in lung, heart and lymphoid tissue
A novel putative G-protein-coupled receptor expressed in lung, heart and lymphoid tissue
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DOI：
10.1016/s0014-5793(97)00278-0
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发表时间：
1997-04-21
期刊：
影响因子：
3.5
通讯作者：
Smeland, EB
中科院分区：
文献类型：
--
作者：
Kvingedal, AM;Smeland, EB
cDNA encoding a novel putative G-protein-coupled receptor, named LyGPR (lymphocyte derived G-protein-coupled receptor) was cloned using a reverse transcription-PCR approach, The LyGPR amino acid sequence is 375 residues long and shows similarity (about 30-35% identity) both to the angiotensin receptors and members of the chemokine receptor family, Northern blot analysis revealed a 3.1-kb LyGPR transcript expressed predominantly in lung, heart and lymphoid tissues, LyGPR expression was also detected in the pre-B acute lymphoblastoid leukemia cell lines Reh and Nalm-6, in the Burkitt's lymphoma line Daudi, and in hematopoietic progenitor cells from bone marrow, as well as in B cells, T cells and monocytes from peripheral blood. (C) 1997 Federation of European Biochemical Societies.
