Epidemiology of Lung Cancer
Epidemiology of Lung Cancer
复制标题
DOI：
10.1055/s-0033-1342949
复制
发表时间：
2013-06-01
影响因子：
1.4
通讯作者：
Ginsberg, Michelle S.
中科院分区：
文献类型：
--
作者：
Ridge, Carole A.;McErlean, Aoife M.;Ginsberg, Michelle S.
自20世纪30年代以来，肺癌的发病率和死亡率一直在稳步上升。改善预后的努力不仅使人们对肺癌的病因有了更多的了解，而且对单个肺癌的组织学和分子特征也有了更好的了解。本文通过讨论当前肺癌流行的范围，包括当代的发病率和死亡率趋势，肺癌发生的危险因素，以及有希望的治疗分子靶点的细节来描述这一演变。
Incidence and mortality attributed to lung cancer has risen steadily since the 1930s. Efforts to improve outcomes have not only led to a greater understanding of the etiology of lung cancer, but also the histologic and molecular characteristics of individual lung tumors. This article describes this evolution by discussing the extent of the current lung cancer epidemic including contemporary incidence and mortality trends, the risk factors for development of lung cancer, and details of promising molecular targets for treatment.