Silica gel microspheres decorated with covalent triazine-based frameworks as an improved stationary phase for high performance liquid chromatography
Silica gel microspheres decorated with covalent triazine-based frameworks as an improved stationary phase for high performance liquid chromatography
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共价三嗪骨架修饰的硅胶微球作为高效液相色谱的改进固定相
DOI：
10.1016/j.chroma.2016.12.082
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发表时间：
2017
影响因子：
4.1
通讯作者：
Zhang Shusheng
中科院分区：
文献类型：
--
作者：
Zhao Wenjie;Hui Kai;Hub Chenchen;Wang Xiaoyu;Yu Ajuan;Zhang Shusheng
本文报道了一种基于共价三嗪骨架修饰的硅胶微球（CTF-SiO2）复合物的新型高效液相色谱固定相。在这种新的杂化材料中，片状共价三嗪基框架（CTF）生长在支撑二氧化硅球上，以实现改进的色谱分离和选择性。采用红外光谱、元素分析、热重分析等手段对材料进行了表征。在反相模式下考察了该固定相的色谱性能和保留机理，并与标准C18柱和氰基改性硅胶（CN-SiO2）柱进行了比较。分析了各种不同的探针分子，包括单取代苯、多环芳烃、苯酚、苯胺和碱。三嗪和芳香基团的协同作用提供了几种不同的保留机制，从而提高了CTF-SiO2复合材料的选择性。均匀的二氧化硅微球良好的柱填充性能与CTF骨架的分离能力相结合，使新的CTF-SiO2材料成为分析复杂样品的潜在有用的固定相。
A new stationary phase for high performance liquid chromatography (HPLC) applications based on silica gel microspheres decorated with covalent triazine-based frameworks (CTF–SiO2) composite has been reported here. In this new hybrid material, sheet-like covalent triazine-based frameworks (CTF) were grown onto the supporting silica spheres, in order to achieve improved chromatographic separation and selectivity. The new material was characterized by infrared spectroscopy, elemental analysis and thermogravimetric analysis. The chromatographic performance and retention mechanism of the new stationary phase were investigated in reversed-phase mode and compared against standard C18and cyano-modified silica (CN–SiO2) columns. A variety of different probe molecules were analyzed, including mono-substituted benzenes, polycyclic aromatic hydrocarbons, phenols, anilines and bases. The synergism of triazine and aromatic moieties provided several different retention mechanisms, thus improving the selectivity in the CTF–SiO2composite. The good column packing properties of the uniform silica microspheres combined with the separation ability of the CTF frameworks make the new CTF–SiO2material a potentially useful stationary phase for the analysis of complex samples.