Copper(II)-Catalyzed Domino Synthesis of 4‑Benzenesulfonyl Isoxazoles from 2‑Nitro-1,3-enynes, Amines, and Sodium Benzenesulfinate
Copper(II)-Catalyzed Domino Synthesis of 4‑Benzenesulfonyl Isoxazoles from 2‑Nitro-1,3-enynes, Amines, and Sodium Benzenesulfinate
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铜(II)催化多米诺合成2-硝基-1,3-烯炔、胺和苯亚磺酸钠4-苯磺酰基异恶唑
DOI：
10.1021/acs.joc.0c01964
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
Yiyuan Peng
中科院分区：
文献类型：
--
作者：
Junying Ge;Qiuping Ding;Xujing Long;Xuan Liu;Yiyuan Peng
A simple and effective method for the synthesis of fully substituted 4-benzenesulfonyl isoxazoles through a copper(II)-catalyzed three-component reaction of 2-nitro-1,3-enynes, amines, and sodium benzenesulfinate is described. The reaction proceeds smoothly under mild conditions and provides the benzenesulfonyl isoxazoles with high chemoselectivity.
