Production of Bioactive Nanomaterial Using Laser Generated Nanoparticles
Production of Bioactive Nanomaterial Using Laser Generated Nanoparticles
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DOI：
10.2961/jlmn.2009.01.0010
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发表时间：
2009-04-01
影响因子：
1.1
通讯作者：
Barcikowski, Stephan
中科院分区：
文献类型：
--
作者：
Hahn, Anne;Barcikowski, Stephan
激光烧蚀被证明是一种有效的工具，以产生高纯度的纳米粒子在液体中设计新的生物活性材料。在我们的研究中，我们提出了一种新的路线来设计生物活性材料，通过纳米复合材料和纳米表面解决两个生物活性效应。纳米粒子在激光烧蚀过程中产生，并使用环境扫描电子显微镜，元素映射（能量色散X射线光谱）和透射电子显微镜进行表征。纳米粒子的大小，生产率和原位功能化的研究在乙酸乙酯作为载体流体嵌入纳米粒子到聚合物。在0.01%和0.1%的硅树脂溶液中原位官能化导致银纳米颗粒生产率的增加。此外，我们发现，NiTi纳米粒子产生化学计量从散装和细胞粘附到纳米表面涂有1 μ g/cm（2）的纳米粒子浓度。总的来说，我们提出了一种基于激光的两种类型的生物活性纳米材料的访问。
Laser ablation is demonstrated as an effective tool to generate highly pure nanoparticles in liquids to design novel bioactive materials. In our study we present a novel route to design bioactive materials addressing two bioactive effects via nanocomposites and nanosurfaces. Nanoparticles are generated during laser ablation and are characterised using environmental scanning electron microscopy, element mapping (energy dispersive X-ray spectroscopy) and transmission electron microscopy. The nanoparticle size, productivity and in-situ functionalisation is investigated in ethylacetate as carrier fluid for embedding nanoparticles into polymers. In-situ functionalisation in 0.01% and 0.1% solution of silicone resin leads to an increase of silver-nanoparticle productivity. Furthermore, we found that NiTi-nanoparticles are generated stoichiometrically from the bulk and that cells adhere onto nanosurfaces coated with a nanoparticle concentration of 1 mu g/cm(2). Overall, we present a laser-based access to two types of bioactive nanomaterials.