Patient reported late effects of gynecological cancer treatment
Patient reported late effects of gynecological cancer treatment
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DOI：
10.1016/j.ygyno.2011.11.034
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发表时间：
2012-03-01
影响因子：
4.7
通讯作者：
Metz, James M.
中科院分区：
文献类型：
--
作者：
Grover, Surbhi;Hill-Kayser, Christine E.;Metz, James M.
目标。在美国，有大量的妇科癌症幸存者生活在他们治疗的长期后遗症中。为了解决生存问题，患者报告的结果对于记录患者的经历是必不可少的；然而，患者报告的毒性并不经常被收集或报告。一个基于网络的生存护理计划工具被用来收集390名接受妇科癌症治疗的妇女的患者报告的毒性数据。对患者的人口学、诊断、治疗方式和毒性资料进行综述。确诊的中位年龄为49岁，88%(n=334)的女性是高加索人，并至少上过一些大学。只有10%(n=38)以前提供了生存护理计划或生存信息。几乎一半的患者患有卵巢癌(46%，n=180)，23%的患者患有宫颈癌(n=92)，28%的患者患有子宫癌(n=109)。对于所有使用该工具的妇科恶性肿瘤幸存者来说，最常见的晚期反应是认知改变、性副作用、肠道模式改变、周围神经病变和皮肤改变。患有妇科癌症的女性经历了过多的后遗症；然而，她们中很少有人有机会获得生存计划来应对这些问题。患者报告的副作用，特别是性功能障碍，比以前报告的更常见。为了全面护理妇科癌症幸存者，需要以患者为中心的工具来评估这些副作用和获得生存计划。(C)2011 Elsevier Inc.保留所有权利。
Objective. There are a large number of gynecological cancer survivors in the United States living with long term sequelae of their treatment. Patient reported outcomes are essential in capturing patients' experiences in order to address survivorship issues; however, patient reported toxicities are not often collected or reported.Methods. A web-based survivorship care plan tool was used to collect patient reported toxicity data for 390 women who had undergone treatment for gynecological cancer. Demographic, diagnosis, treatment modality and toxicity data were reviewed.Results. Median age of diagnosis was 49 years, and 88% (n = 334) of the women were Caucasian and had attended at least some college. Only 10% (n = 38) had previously been offered a survivorship care plan or survivorship information. Almost half of the patients had ovarian cancer (46%, n = 180), 23% had cervical cancer (n = 92) and 28% had uterine cancer (n = 109). Late effects most commonly reported for all gynecological malignancy survivors using this tool were cognitive changes, sexual side effects, changes in bowel patterns, peripheral neuropathy and skin changes.Conclusion. Women with gynecological cancers experience a plethora of late effects; however, very few of them have access to a survivorship plan to cope with these issues. Patient reported side effects, especially sexual dysfunction, occur more commonly than previously reported. Patient-focused tools to evaluate these side effects and access to survivorship plans are needed for comprehensive care of gynecologic cancer survivors. (C) 2011 Elsevier Inc. All rights reserved.