Investigation of human brain hemodynamics by simultaneous near-infrared spectroscopy and functional magnetic resonance imaging
Investigation of human brain hemodynamics by simultaneous near-infrared spectroscopy and functional magnetic resonance imaging
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DOI：
10.1118/1.1354627
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发表时间：
2001-04-01
期刊：
影响因子：
3.8
通讯作者：
Hueber, D
中科院分区：
文献类型：
--
作者：
Toronov, V;Webb, A;Hueber, D
本研究的目的是比较功能脑血流动力学信号同时获得近红外光谱（NIRS）和功能磁共振成像（fMRI）。还评估了浅表层（皮肤和颅骨）对NIRS信号的贡献。这两种方法都被用来生成功能地图的运动皮层区域在一个周期性序列的刺激手指运动和休息。在所有受试者中，我们发现了一个很好的搭配的大脑活动中心揭示了这两种方法。我们还发现，BOLD信号（功能磁共振成像）和脱氧血红蛋白浓度（NIRS）的受试者谁表现出低波动的浅表头部组织之间的时间相关性高。(C)2001年美国医学物理学家协会。
The aim of this study was to compare functional cerebral hemodynamic signals obtained simultaneously by near infrared spectroscopy (NIRS) and by functional magnetic resonance imaging (fMRI). The contribution of superficial layers (skin and skull) to the NIRS signal was also assessed. Both methods were used to generate functional maps of the motor cortex area during a periodic sequence of stimulation by finger motion and rest. In all subjects we found a good collocation of the brain activity centers revealed by both methods. We also found a high temporal correlation between the BOLD signal (fMRI) and the deoxy-hemoglobin concentration (NIRS) in the subjects who exhibited low fluctuations in superficial head tissues. (C) 2001 American Association of Physicists in Medicine.