PERCUTANEOUS ETHANOL INJECTION FOR THE TREATMENT OF SMALL HEPATOCELLULAR-CARCINOMA - STUDY OF 95 PATIENTS
PERCUTANEOUS ETHANOL INJECTION FOR THE TREATMENT OF SMALL HEPATOCELLULAR-CARCINOMA - STUDY OF 95 PATIENTS
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DOI：
10.1111/j.1440-1746.1990.tb01115.x
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发表时间：
1990-11-01
影响因子：
4.1
通讯作者：
KONDO, Y
中科院分区：
文献类型：
--
作者：
EBARA, M;OHTO, M;KONDO, Y
近6年来，对95例小于3cm的肝细胞癌（HCC）患者的120个病灶进行了经皮乙醇注射（PEI）治疗。 PEI 后 67 名接受超声检查超过 6 个月的患者中，所有主要目标肿瘤的大小均有所缩小； 28 个肿瘤（41.8%）变得无法检测到，并且一直保持到现在。采用Kaplan-Meier法计算的1年、2年、3年、4年和5年生存率分别为93%、81%、65%、52%和28%。这些生存率优于未接受抗癌治疗的小于3 cm HCC 患者的生存率（P < 0.01）。 Child's A 或 Child's B 状态患者的生存率优于 Child's C 疾病患者。 PEI 后一年内复发的比例为 34%，两年内复发的比例为 61%，三年内复发的比例为 66%。然后对 61% 的此类患者重复进行 PEI。
Percutaneous ethanol injection (PEI) was applied to 120 lesions in 95 patients with hepatocellular carcinomas (HCC) smaller than 3 cm in the past 6 years. All main target tumours, in 67 patients who had been followed by sonography for more than 6 months after PEI, decreased in size; 28 tumours (41.8%) became undetectable and have remained so until now. The 1-, 2-, 3-, 4- and 5-year survival rates calculated by the Kaplan-Meier method were 93%, 81%, 65%, 52% and 28% respectively. These survival rates were better than those of patients with HCC smaller than 3 cm who did not receive anticancer treatment (P < 0.01). The survival of patients of the Child's A or Child's B status was better than that of those with Child's C disease. Recurrence occurred in areas within the liver different from the original lesion in 34% in one year, 61% in two years and 66% in three years after PEI. PEI was then repeated in 61% of such patients.