Extrageniculate mediation of unconscious vision in transcranial magnetic stimulation-induced blindsight.
Extrageniculate mediation of unconscious vision in transcranial magnetic stimulation-induced blindsight.
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经颅磁刺激诱发盲视中无意识视觉的外基因调节。
DOI：
10.1073/pnas.0403061101
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发表时间：
2004
影响因子：
11.1
通讯作者：
E. Chang
中科院分区：
文献类型：
--
作者：
T. Ro;Dominique Shelton;Olivia L Lee;E. Chang
所提出的支持盲视的神经机制，即皮质盲患者在强制选择视觉辨别任务中的上述机会表现，是有争议的。在本文中，我们表明，尽管当视觉皮层上的经颅磁刺激引起暗点时，受试者无法感知中心凹呈现的视觉刺激，但在定向扫视中，这些无意识的干扰物会显着延迟反应，但在间接手动反应任务中则不会。这些结果表明，与感觉编码以及扫视眼运动的产生有关的上丘正在介导经颅磁刺激抑制的干扰物的无意识处理，并暗示视网膜顶盖通路在许多盲视现象中的作用。
The proposed neural mechanisms supporting blindsight, the above-chance performance of cortically blind patients on forced-choice visual discrimination tasks, are controversial. In this article, we show that although subjects were unable to perceive foveally presented visual stimuli when transcranial magnetic stimulation over the visual cortex induced a scotoma, responses nonetheless were delayed significantly by these unconscious distractors in a directed saccade but not in an indirect manual response task. These results suggest that the superior colliculus, which is involved with sensory encoding as well as with the generation of saccadic eye movements, is mediating the unconscious processing of the transcranial magnetic stimulation-suppressed distractors and implicate a role of the retinotectal pathway in many blindsight phenomena.