How often are nonenhancing supratentorial gliomas malignant? A population study

How often are nonenhancing supratentorial gliomas malignant? A population study
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DOI:
10.1212/wnl.59.6.947
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发表时间:
2002-09-24
期刊:
影响因子:
9.9
通讯作者:
Forsyth, PA
Forsyth, PA
中科院分区:
医学1区
文献类型:
--
作者:
Scott, JN;Brasher, PMA;Forsyth, PA

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脑肿瘤中对比度增强的存在通常被认为是恶性肿瘤的标志。作者在未经选择的人群中鉴定了 314 名患有恶性和低度幕上神经胶质肿瘤的患者,其中 58 名患者术前神经影像学缺乏对比增强。大约三分之一的非增强性神经胶质瘤是恶性的,尤其是老年患者。因此,对于所有怀疑患有原发性神经胶质肿瘤的患者,组织学确认诊断非常重要。
The presence of contrast enhancement in a brain tumor is often regarded as a sign of malignancy. The authors identified 314 patients with malignant and low-grade supratentorial glial neoplasms in an unselected population, 58 of which lacked contrast enhancement on preoperative neuroimaging. Nonenhancing gliomas were malignant in approximately one third of cases, especially in older patients. Histologic confirmation of the diagnosis is therefore important in all patients suspected of harboring a primary glial neoplasm.