Association of Summer Temperatures With Hospital Admissions for Renal Diseases in New York State: A Case-Crossover Study

Association of Summer Temperatures With Hospital Admissions for Renal Diseases in New York State: A Case-Crossover Study
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DOI:
10.1093/aje/kwr417
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发表时间:
2012-05-01
影响因子:
5
通讯作者:
Hwang, Syni-An
Hwang, Syni-An
中科院分区:
医学2区
文献类型:
--
作者:
Fletcher, Barbara A.;Lin, Shao;Hwang, Syni-An

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这项研究评估了高温与肾脏疾病住院几率增加之间的关系,到目前为止,只有少量研究对此进行了研究。采用病例交叉设计研究了纽约州1991年7月至2004年8月间147,885例因肾脏疾病入院的患者。来自自动监测仪的区域温度、湿度和气压数据被用作暴露指标。通过时间分层参照选择和条件Logistic回归分析,发现平均气温滞后1天,每5华氏度(2.78摄氏度)急性肾功能衰竭住院的几率增加9%(优势比=1.09,95%可信区间:1.07,1.12)。结果表明,黑人、西班牙裔、25-44岁的人和收入最低的四分位数的人因急性肾功能衰竭住院的易感性增加。几率因地理位置不同而不同,最大的关联出现在更多的城市地区。尿路感染、肾结石、下尿路结石和其他下尿路疾病的住院几率也增加。这些发现有助于确定脆弱的亚群,并为有关适应战略和高温预警系统的决策和政策提供信息。
This study assessed the association between high temperatures and increased odds of hospitalization for renal diseases that, to date, has been examined in only a small number of studies. A case-crossover design was used to study 147,885 hospital admissions with renal diagnoses during July and August, 1991-2004, in New York State. Regional temperature, humidity, and barometric pressure data from automated monitors were used as exposure indicators. By use of time-stratified referent selection and conditional logistic regression analysis, an overall 9% increase in odds of hospitalization for acute renal failure per 5 degrees F (2.78 degrees C) was found for mean temperature at a 1-day lag (odds ratio = 1.09, 95% confidence interval: 1.07, 1.12). The results suggest increased susceptibility to hospitalization for acute renal failure for blacks, Hispanics, people aged 25-44 years, and those in the lowest income quartile. The odds varied geographically with the largest associations found in the more urban regions. Increased odds of hospitalization were also found for urinary tract infections, renal calculi, lower urinary calculi, and other lower urinary tract disorders. The findings can help to identify vulnerable subpopulations and to inform decisions and policies regarding adaptation strategies and heat-warning systems.