Magnetic resonance imaging for distinguishing ovarian clear cell carcinoma from high-grade serous carcinoma.
Magnetic resonance imaging for distinguishing ovarian clear cell carcinoma from high-grade serous carcinoma.
复制标题
磁共振成像用于区分卵巢透明细胞癌和高级别浆液性癌
DOI：
10.1186/s13048-016-0251-x
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发表时间：
2016-07-04
影响因子：
4
通讯作者：
Rao YM
中科院分区：
文献类型：
--
作者：
Ma FH;Qiang JW;Zhang GF;Li HM;Cai SQ;Rao YM
目的比较卵巢透明细胞癌（CCC）和高级别浆液性癌（HGSC）的MRI表现，以鉴别CCC和HGSC。（偏侧性、形态、大小、构型、乳头状突起、信号强度、强化、腹膜种植、淋巴结肿大、腹水）对37例CCC患者的40个肿瘤进行分析，经手术病理证实，与40例HGSC患者的62个肿瘤进行比较。结果CCC与HGSC的最大径、偏侧性及FIGO分期差异均有统计学意义（P= 0. 002，P <0. 001，P <0. 001）。与HGSC相比，CCC更常见于椭圆形（30/40，75% vs 12/62，19%;P< 0.001），更常见于囊性（21/40，53% vs 8/62，13%;P< 0.001）和单房性（23/29，79%vs7/31，23%，P< 0.001），T1高信号囊性成分更常见（18/29，62%vs5/29，17%，P< 0.001），乳头状突起增大（5.13 ± 0.4cm对2.91 ± 0.3cm; P< 0.001），腹膜植入频率较低结论CCC表现为椭圆形、单房囊性肿块，伴有大乳头状突起和T1高信号。MRI有助于CCC与HGSC的鉴别。
BackgroundTo compare the magnetic resonance imaging (MRI) features of ovarian clear cell carcinoma (CCC) and high-grade serous carcinoma (HGSC), to distinguish CCC from HGSC.MethodsMRI features (laterality, shape, size, configuration, papillary projection, signal intensity, enhancement, peritoneal implant, lymphadenopathy, ascites) of 40 tumors in 37 patients with CCC, confirmed by surgery and pathology, were compared with those of 62 tumors in 40 patients with HGSC. Statistical analysis was performed using Mann-Whitney and Fisher’s exact tests.ResultsThere was a statistically significant difference in the mean maximum diameter, laterality, and FIGO stage (P= 0.002,P< 0.001,P< 0.001, respectively) between CCC and HGSC. Compared to HGSCs, CCCs were more frequently oval (30/40, 75 % vs 12/62, 19 %;P< 0.001), more often cystic (21/40, 53 % vs 8/62, 13 %;P< 0.001) and unilocular (23/29, 79 % vs 7/31, 23 %;P< 0.001), had T1-hyperintense cystic components more often (18/29, 62 % vs 5/29, 17 %;P< 0.001), had larger papillary projections (5.13 ± 0.4 cm vs 2.91 ± 0.3 cm;P< 0.001), were peritoneally implanted less frequently (P= 0.001) and had fewer ascites (P< 0.001).ConclusionsCCC typically showed an oval, unilocular cystic mass with large papillary projection and T1-hyperintense cystic components. MRI could be helpful for distinguishing CCC from HGSC.