ESTROGEN USE AND VERBAL MEMORY IN HEALTHY POSTMENOPAUSAL WOMEN
ESTROGEN USE AND VERBAL MEMORY IN HEALTHY POSTMENOPAUSAL WOMEN
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DOI：
10.1097/00006250-199406000-00017
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发表时间：
1994-06-01
影响因子：
7.2
通讯作者：
SHERWIN, BB
中科院分区：
文献类型：
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作者：
KAMPEN, DL;SHERWIN, BB
目的：评估一组健康、功能正常的绝经后社区妇女的言语记忆差异是否与雌激素的使用有关。方法：对来自普通人群的健康绝经后妇女进行言语和空间记忆、语言、注意力和一般空间技能的测试。将服用雌激素的女性与没有服用任何形式的雌激素替代疗法的同一人群中的女性进行比较。结果：服用雌激素的女性和不服用雌激素的女性在任何社会人口学变量上都没有差异。然而，服用雌激素的女性在即刻和延迟段落回忆测试中的得分显著高于不服用雌激素的女性。在其他认知功能测试上，包括空间记忆测试，没有明显的差异。结论：雌激素似乎对健康绝经后女性的言语记忆技能有特定的影响。这些发现对健康的老年女性的临床相关性仍有待确定。
Objective: To assess whether differences in verbal memory might be related to estrogen use in a group of healthy, well-functioning, postmenopausal community-residing women from a broad socioeconomic range.Methods: Healthy postmenopausal women drawn from the general population were given tests of verbal and spatial memory, language, attention, and general spatial skills. The performance of women taking estrogen was compared to that of women from the same population who were not taking any form of estrogen replacement therapy.Results: There were no differences between the estrogen users and non-users on any sociodemographic variables. However, the Scores of women taking estrogen were significantly higher on tests of immediate and delayed paragraph recall compared to the scores of non-users. No differences were apparent on other tests of cognitive functioning, including tests of spatial memory.Conclusion: Estrogen appears to have a specific effect on verbal memory skills in healthy postmenopausal women. The clinical relevance of these findings for healthy older women remains to be determined.