Anopheles darlingi (Diptera: Culicidae) displays increased attractiveness to infected individuals with Plasmodium vivax gametocytes
Anopheles darlingi (Diptera: Culicidae) displays increased attractiveness to infected individuals with Plasmodium vivax gametocytes
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DOI：
10.1186/1756-3305-7-251
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发表时间：
2014-05-29
影响因子：
3.2
通讯作者：
Silva, Alexandre A.
中科院分区：
文献类型：
--
作者：
Batista, Elis P. A.;Costa, Elizangela F. M.;Silva, Alexandre A.
背景：大多数吸血昆虫利用宿主气味作为化学线索。昆虫的气味成分、某些生理参数和对寄主的吸引力受多种条件的影响，包括寄生虫的感染，如：例如，在一个实施例中，疟原虫，从而改变流行病学的情况。这项研究评估了个人与间日疟的吸引力之前，期间（7天）和治疗后（14天）与特定的抗疟drugs.Findings：Moscovirus间日疟感染的患者的吸引力进行了评估，使用垂直嗅觉仪使用脚作为一个来源的体臭。使用嗅觉计下室中的达氏按蚊的比率来计算吸引力，并使用数字温度计测量患者温度。在第一次实验（早期感染）中，仅在携带间日疟原虫配子体的患者中发现吸引力增加（P < 0.001）。第一个实验中的患者往往体温较高，但将患者分为发烧和非发烧组，仅在配子母细胞携带者发烧组中产生了更高的吸引力，这表明温度和配子母细胞在宿主吸引力中具有协同作用。A.结论：间日疟患者配子体的存在和发热增加了近距离宿主对疟原虫的吸引力。亲爱的
Background: Most hematophagous insects use host odours as chemical cues. The odour components, some physiological parameters and host attractiveness are affected by several conditions, including infection by parasites, e. g., plasmodia and, therefore, change the epidemiological scenario. This study evaluated the attractiveness of individuals with vivax malaria before, during (7 days) and after treatment (14 days) with specific antimalarial drugs.Findings: Mosquito attractiveness to vivax-infected patients was assessed using a vertical olfactometer using the foot as a source of body odour. The ratio of Anopheles darlingi mosquitoes in the lower chamber of the olfactometer was used to calculate the attractiveness, and patient temperature was measured using a digital thermometer. An increased attractiveness was found only in patients bearing vivax gametocytes during the first experiment (early infection) (P < 0.001). Patients in the first experiment tended to have a higher body temperature, but grouping patients into fever and non-fever resulted in a higher attractiveness only in the fever group of gametocyte carriers, suggesting a synergistic effect of temperature and gametocytes in the host attractiveness to A. darlingi.Conclusions: Gametocyte presence and fever in vivax malaria patients increased short distance host attractiveness to An. darlingi.