A combined nanoplasmonic and electrodeless quartz crystal microbalance setup.
A combined nanoplasmonic and electrodeless quartz crystal microbalance setup.
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DOI：
10.1063/1.3265321
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发表时间：
2009-12
期刊：
影响因子：
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通讯作者：
E. M. Larsson;M. Edvardsson;C. Langhammer;I. Zorić;B. Kasemo
中科院分区：
文献类型：
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作者：
E. M. Larsson;M. Edvardsson;C. Langhammer;I. Zorić;B. Kasemo
我们研制了一种将局域表面等离子体共振(LSPR)传感与无电极石英晶体微天平和耗散监测(QCM-D)相结合的仪器。这两种技术可以同时运行，在相同的传感器表面上，具有与单独技术相同的时间分辨率和灵敏度。无电极QCM消除了在石英晶体上制造电极的需要，并为QCM-D和LSPR在选择表面结构和涂层方面提供了很大的灵活性。在脂类双层形成和生物识别事件的液相测量以及钯纳米颗粒的氢吸收/释放的气相测量中证明了该方法的性能。使用组合设备进行生物分子吸附研究的优点包括关于结构转变和分子(干)质量的提取以及附着层的水化程度的同步信息，这是单独使用技术无法获得的。在氢气存储研究中，组合设备允许同步测量吸收/释放动力学，并在实际有趣的氢气压力和温度下量化纳米颗粒和薄膜中存储的氢气量。
We have developed an instrument combining localized surface plasmon resonance (LSPR) sensing with electrodeless quartz crystal microbalance with dissipation monitoring (QCM-D). The two techniques can be run simultaneously, on the same sensor surface, and with the same time resolution and sensitivity as for the individual techniques. The electrodeless QCM eliminates the need to fabricate electrodes on the quartz crystal and gives a large flexibility in choosing the surface structure and coating for both QCM-D and LSPR. The performance is demonstrated for liquid phase measurements of lipid bilayer formation and biorecognition events, and for gas phase measurements of hydrogen uptake/release by palladium nanoparticles. Advantages of using the combined equipment for biomolecular adsorption studies include synchronized information about structural transformations and extraction of molecular (dry) mass and degree of hydration of the adlayer, which cannot be obtained with the individual techniques. In hydrogen storage studies the combined equipment, allows for synchronized measurements of uptake/release kinetics and quantification of stored hydrogen amounts in nanoparticles and films at practically interesting hydrogen pressures and temperatures.