Relationship between Air Pollution and Outpatient Visits for Nonspecific Conjunctivitis
Relationship between Air Pollution and Outpatient Visits for Nonspecific Conjunctivitis
复制标题
DOI：
10.1167/iovs.11-8253
复制
发表时间：
2012-01-01
影响因子：
4.4
通讯作者：
Tsai, Hsien-Yang
中科院分区：
文献类型：
--
作者：
Chang, Chia-Jen;Yang, Hsi-Hsien;Tsai, Hsien-Yang
目的。过去的研究提供了空气污染与人类眼部症状之间关联的证据；然而，据作者所知，尚不存在调查空气污染对非特异性结膜炎有害影响的研究。本研究调查了台湾空气污染与非特异性结膜炎门诊就诊之间的关系。进行多区域分析来检查和评估颗粒物（PM）、二氧化氮（NO2）、二氧化硫（SO2）、臭氧（O-3）和一氧化碳对非特异性结膜炎的短期影响的风险。方法。数据来自七个空气质量监测区域的非特异性结膜炎门诊患者。为了发现空气污染的即时和滞后影响，进行了特定区域的病例交叉分析，并使用随机效应的荟萃分析来结合特定区域的结果。结果。 O-3 和 NO2 对非特异性结膜炎门诊就诊的影响最强，O-3 浓度增加 16.4 ppb（十亿分之一）时，增加 2.5%（95% 置信区间 [CI]，0.9-4.1）；NO2 浓度增加 11.47 ppb 时，增加 2.3%（95% CI，0.7-3.9）。还发现了具有空气动力学直径的颗粒物的影响
PURPOSE. Past studies present evidence of associations between air pollution and human ocular symptoms; however, to the knowledge of the authors, research investigating the hazardous effects of air pollution on nonspecific conjunctivitis is nonexistent. This study investigates the relationship between air pollution and outpatient visits for nonspecific conjunctivitis in Taiwan. A multiarea analysis was conducted to examine and assess the risks of short-term effects of particulate matter (PM), nitrogen dioxide (NO2), sulfur dioxide (SO2), ozone (O-3), and carbon monoxide on nonspecific conjunctivitis.METHODS. Data were collected from outpatient visits for nonspecific conjunctivitis from seven air-quality-monitoring areas. To find immediate and lag effects of air pollution, an area-specific, case-crossover analysis was performed and a meta-analysis with random effects was used to combine the area-specific results.RESULTS. The effects on outpatient visits for nonspecific conjunctivitis are strongest for O-3 and NO2, with a 2.5% increase (95% confidence interval [CI], 0.9-4.1) for a 16.4 ppb (parts per billion) concentration rise in O-3 and a 2.3% increase (95% CI, 0.7-3.9) for an 11.47 ppb concentration rise in NO2. Effects are also found for particulate matter with an aerodynamic diameter