Natural history of food allergy in infants and children in Israel
Natural history of food allergy in infants and children in Israel
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DOI：
10.1016/s1081-1206(10)60228-1
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发表时间：
2008-12-01
影响因子：
5.9
通讯作者：
Dalal, Ilan
中科院分区：
文献类型：
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作者：
Aaronov, Darit;Tasher, Diana;Dalal, Ilan
背景：关于食物过敏的自然历史，特别是芝麻过敏的知识很少。目的：了解以色列食物过敏的自然历史，特别是芝麻过敏。方法：对诊断为食物过敏的儿童进行临床记录和详细问卷调查。结果：发现234名疑似食物过敏的儿童。在180名确诊患者（77%）中检测出283例过敏。最常见的过敏是牛奶（125），鸡蛋（71），芝麻（30）和大豆（23）。在牛奶过敏患者中，69%是IgE介导的（第一组），31%是非IgE介导的（第二组）。1组比2组更有可能有特应性背景（P = 0.003），而2组更有可能有过敏消退(2组39例中有35例[90%]，而1组86例中只有32例[37%]，P
Background: Knowledge about the natural history of food allergy, especially sesame, is scarce.Objective: To follow the natural history of food allergies in Israel, particularly of sesame allergy.Methods: The Survey was conducted based on clinical records and a detailed questionnaire of children diagnosed as having food allergy.Results: We found 234 children with suspected food allergy. Testing detected 283 allergies in 180 patients (77%) with confirmed diagnosis. The most common allergies were to cow's milk (n = 125), eggs (n = 71), sesame (n = 30), and soy (n 23). Of those with milk allergy, 69% were IgE mediated (group 1) and 31% were non-IgE mediated (group 2). Group I was more likely to have an atopic background than was group 2 (P =.003), whereas group 2 was more likely to have resolution of the allergy (35 of 39 [90%] in group 2 compared with only 32 of 86 [37%] in group 1, P