Development and validation of a questionnaire to measure asthma control
Development and validation of a questionnaire to measure asthma control
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DOI：
10.1034/j.1399-3003.1999.14d29.x
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发表时间：
1999-10-01
影响因子：
24.3
通讯作者：
King, DR
中科院分区：
文献类型：
--
作者：
Juniper, EF;O'Byrne, PM;King, DR
哮喘管理国际指南表明，治疗的首要目标应该是最佳的哮喘控制。本研究的目的是开发和验证哮喘控制问卷 (ACQ)。作者生成了一份用于评估控制情况的所有症状清单，并将其发送给 100 名哮喘临床医生，他们是指南委员会的成员（18 个国家）。他们对每种症状在评估哮喘控制方面的重要性进行了评分。从 91 个回复中，选择了得分最高的 5 个症状进行 ACQ。此外，还有一个关于 β(2) 激动剂使用的问题和另一个关于气道口径的问题（总问题 = 7）。 ACQ 在一项为期 9 周的观察性研究中进行了测试，该研究对 50 名患有症状性哮喘的成人进行了测试，在基线、第 1、5 和 9 周评估了 ACQ 和哮喘健康状况的其他指标。在两次就诊之间哮喘稳定的患者中，ACQ 的可靠性很高（组内相关系数 (ICC)=0.90）。问卷对哮喘控制的变化非常敏感（p
International guidelines on asthma management indicate that the primary goal of treatment should be optimum asthma control. The aim of this study was to develop and validate the Asthma Control Questionnaire (ACQ).The authors generated a list of all symptoms used to assess control and sent it to 100 asthma clinicians who were members of guidelines committees (18 countries). They scored each symptom for its importance in evaluating asthma control. From the 91 responses, the five highest scoring symptoms were selected for the ACQ. In addition, there is one question on beta(2)-agonist use and another on airway calibre (total questions=7). The ACQ was tested in a 9-week observational study of 50 adults with symptomatic asthma, The ACQ and other measures of asthma health status were assessed at baseline, 1, 5 and 9 weeks.In patients whose asthma was stable between clinic visits, reliability of the ACQ was high (intraclass correlation coefficient (ICC)=0.90). The questionnaire was very responsive to change in asthma control (p