Relationship of health-related quality of life to symptom severity in diabetes mellitus: A study in Trinidad and Tobago
Relationship of health-related quality of life to symptom severity in diabetes mellitus: A study in Trinidad and Tobago
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DOI：
10.1016/s0895-4356(99)00053-0
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发表时间：
1999-08-01
影响因子：
7.2
通讯作者：
Mahabir, D
中科院分区：
文献类型：
--
作者：
Gulliford, MC;Mahabir, D
我们的目标是在特立尼达的35个政府初级保健保健中心进行横断面设计，评估糖尿病症状严重程度对与健康相关的生活质量测量的影响。收集了2,117例临床糖尿病患者的数据，并对其中1,880例(%)进行了分析。对于简表36问卷(SF-36)的每个量表(与健康相关的生活质量的通用测量)，分数以症状严重程度的四分位数表示，使用糖尿病症状检查表进行测量。SF-36平均得分(SD)为身体部分(PCS)44分(10)，精神部分(MCS)45分(12)。糖尿病症状越严重，SF-36各分量表得分越低。比较DSC评分的最低和最高四分位数，PCS的调整后差异为-11(95%可信区间为-12至-9)，MCS-16的调整后差异为-18至-14。我们的结果提供了与糖尿病疾病严重程度相关的健康相关生活质量的标准化数据，这些数据可能被用来帮助评估相关干预措施。《CLIN流行病学杂志》52；8：773-780,1999。(C)1999年爱思唯尔科学公司。
Our objective was to estimate the effect of greater symptom severity in diabetes mellitus on measures of health-related quality of life in a cross-sectional design in 35 government primary care health centres in Trinidad. Data were gathered on 2,117 subjects with clinical diabetes and analysed for 1,880 (89%). For each scale of the short form 36 (SF-36) questionnaire (a generic measure of health-related quality of life), scores were presented by quartile of symptom severity, measured using the Diabetes Symptom Checklist. Mean (SD) SF-36 scores were 44 (10) for the physical component score (PCS) and 45 (12) for the mental component score (MCS). Greater severity of diabetic symptoms was associated with lower scores on each of the subscales of the SF-36. Comparing lowest and highest quartiles of DSC score, the adjusted difference in PCS was -11 (95% confidence interval -12 to -9) and for MCS -16 (-18 to -14). Our results provide standardised data for health related quality of life in relation to severity of illness from diabetes, these might be used to aid the evaluation of relevant interventions. J CLIN EPIDEMIOL 52;8:773-780, 1999. (C) 1999 Elsevier Science Inc.