Aspergillus nidulans stcP encodes an o-methyltransferase that is required for sterigmatocystin biosynthesis
Aspergillus nidulans stcP encodes an o-methyltransferase that is required for sterigmatocystin biosynthesis
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DOI：
10.1128/aem.62.11.4296-4298.1996
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发表时间：
1996-11-01
影响因子：
4.4
通讯作者：
Adams, TH
中科院分区：
文献类型：
--
作者：
Kelkar, HS;Keller, NP;Adams, TH
The Aspergillus nidulans stcP gene was previously identified as a transcribed region associated with a cluster of genes proposed to be involved in sterigmatocystin biosynthesis (D. W. Brown, J.-H. Yu, H. S. Kelkar, M. Fernandes, T. C. Nesbitt, N. P. Keller, T. H. Adams, and T. J. Leonard, Proc. Natl. Acad. Sci, USA 93:1418-1422, 1996), stcP was predicted to encode a methyltransferase responsible for conversion of demethylsterigmatocystin to sterigmatocystin. Here we demonstrate that disruption of stcP in A, nidulans results in strains that accumulate demethylsterigmatocystin.
