ABSORPTION AND BIOLOGICAL HALF-LIFE IN HUMANS OF INTRINSIC AND EXTRINSIC MN-54 TRACERS FROM FOODS OF PLANT-ORIGIN
ABSORPTION AND BIOLOGICAL HALF-LIFE IN HUMANS OF INTRINSIC AND EXTRINSIC MN-54 TRACERS FROM FOODS OF PLANT-ORIGIN
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DOI：
10.1093/jn/121.5.711
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发表时间：
1991-05-01
影响因子：
4.2
通讯作者：
KORYNTA, ED
中科院分区：
文献类型：
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作者：
JOHNSON, PE;LYKKEN, GI;KORYNTA, ED
吸收和生物半衰期的Mn-54测定成年男性和女性的食物标记的内在或extraperitoneal与Mn-54。 每名受试者食用一系列的三种测试餐，包括以随机顺序供应的标记为固有的食物、标记为额外的食物或MnCl 2（对照）。 测试的食物有生菜、菠菜、小麦和向日葵籽。 膳食及其对照组中锰含量为9.65 μ mol，其它膳食中锰含量为22.50 μ mol。 除了测试食物或MnCl 2之外，每餐由植物油（5g）、盐（NaCl，0.15g）和饼干（10 g）组成，其提供0.55 μ mol Mn。 对于任何内在/外在标记的食物对，Mn-54的Mn吸收百分比或生物半衰期均无差异。 MnCl_2对~（54）Mn的吸收率（8.90%）高于莴苣（5.20%）、菠菜（3.81%）、小麦（2.16%）和向日葵籽（1.71%），但生物半衰期不随Mn的来源而变化。 莴苣对Mn-54的吸收显著高于小麦和向日葵种子。 虽然锰的剂量在测试餐是生菜比其他食物少，有没有差异，从氯化锰的吸收受试者之间的生菜和受试者喂其他食物。 Mn-54吸收或生物半衰期与全血或血浆Mn均无相关性。
Absorption and biological half-life of Mn-54 were measured in adult men and women fed foods labeled intrinsically or extrinsically with Mn-54. Each subject consumed a series of three test meals consisting of a food labeled intrinsically, a food labeled extrinsically or MnCl2 (control) served in random order. The foods tested were lettuce, spinach, wheat and sunflower seeds. Lettuce meals and their controls contained 9.65-mu-mol Mn; other meals contained 22.50-mu-mol Mn. In addition to the test food or MnCl2, each meal consisted of vegetable oil (5 g), salt (NaCl, 0.15 g) and crackers (10 g), which provided 0.55-mu-mol Mn. There were no differences in percentage of Mn absorption or biological half-life of Mn-54 for any of the intrinsically/extrinsically labeled food pairs. Absorption of Mn-54 from MnCl2 (8.90%) was greater than from lettuce (5.20%), spinach (3.81%), wheat (2.16%) or sunflower seeds (1.71%), but the biological half-life did not vary with the source of Mn. Absorption of Mn-54 from lettuce was significantly (P < 0.05) greater than from wheat or sunflower seeds. Although the Mn dose in the test meal was less for lettuce than for the other foods, there was no difference in Mn absorption from MnCl2 between the subjects fed lettuce and subjects fed other foods. There was no correlation of either Mn-54 absorption or biological half-life with whole blood or plasma Mn.