Evaluation of Quantitative Measurement Techniques for Head Tremor With Thalamic Deep Brain Stimulation
Evaluation of Quantitative Measurement Techniques for Head Tremor With Thalamic Deep Brain Stimulation
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DOI：
10.1111/ner.12566
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发表时间：
2017-07-01
期刊：
影响因子：
2.8
通讯作者：
Pilitsis, Julie
中科院分区：
文献类型：
--
作者：
Chockalingam, Arun;Boggs, Hans;Pilitsis, Julie
研究背景中央丘脑深部电刺激(VIM DBS)治疗难治性特发性震颤(ET)安全有效。我们使用智能帽子和智能手机应用程序来评估定量震颤测量方法在ET中的应用。采用临床金标准Fahn-Tolosa-Marin震颤评定量表(TRS)测量刺激前后的头部和手臂震颤。然后将结果与两种定量测量技术进行比较：Lift Pulse(智能手机应用程序)和Modify Nizet(Nizet等人的改编激光点数测量)。结果Lift脉搏震颤严重度测量值与头部TRS值显著相关(=0.53，p
BackgroundVentralis intermedius thalamic deep brain stimulation (VIM DBS) has shown to be safe and effective for medically refractory essential tremor (ET). We evaluate the use of quantitative tremor measurement methods for head tremor in ET using a smart hat and a smartphone application.MethodsWe enrolled 13 ET patients who previously underwent VIM DBS. Head and arm tremor was measured ON and OFF stimulation using the clinical gold standard Fahn-Tolosa-Marin Tremor Rating Scale (TRS). Results were then compared to two quantitative measurement techniques: Lift Pulse (smartphone application) and modified Nizet (adapted laser point measurement from Nizet et al.). Spearman's rank correlation was used to compare tremor severity and improvement on stimulation using TRS and quantitative methods to measure tremor.ResultsLift Pulse tremor severity measurement significantly correlated with TRS for head (=0.53, p