Relationship between pluronic block copolymer structure, critical micellization concentration and partitioning coefficients of low molecular mass solutes
Relationship between pluronic block copolymer structure, critical micellization concentration and partitioning coefficients of low molecular mass solutes
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DOI：
10.1021/ma991634x
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发表时间：
2000-05-02
期刊：
影响因子：
5.5
通讯作者：
Kabanov, AV
中科院分区：
文献类型：
--
作者：
Kozlov, MY;Melik-Nubarov, NS;Kabanov, AV
以芘和荧光素的同系物作为荧光探针，研究了疏水性溶质在Pluronic嵌段共聚物（聚环氧乙烷-嵌段-聚环氧丙烷-嵌段-聚环氧乙烷）水分散液中的分配系数。一个增量的方法开发，允许测量的自由能转移的亚甲基基团从水介质中的胶束。建立了Pluronic分子中环氧乙烷（EO）和环氧丙烷（PO）嵌段长度变化对溶质分配特性的影响。溶质的分配系数和临界胶束化浓度之间的一个简单的倒数关系被证明。
Using pyrene and homologous alkyl derivatives of fluorescein as fluorescent probes, this work examines the partitioning coefficients of hydrophobic solutes in aqueous dispersions of Pluronic block copolymers (poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(ethylene oxide)). An incremental approach is developed, allowing measurement of the free energy of transfer of a methylene group from aqueous media into the micelles. Effects of variation of length of the ethylene oxide (EO) and the propylene oxide (PO) blocks in Pluronic molecules on the partitioning characteristics of the solutes are established. A simple reciprocal relationship between partitioning coefficients of the solute and critical micellization concentration is demonstrated.