Characterisation of two new radiochromic gel dosimeters TruView™ and ClearView™ in combination with the vista™ optical CT scanner: A feasibility study
Characterisation of two new radiochromic gel dosimeters TruView™ and ClearView™ in combination with the vista™ optical CT scanner: A feasibility study
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DOI：
10.1016/j.ejmp.2018.07.002
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发表时间：
2018-08-01
影响因子：
3.4
通讯作者：
Clairand, I
中科院分区：
文献类型：
--
作者：
Colnot, J.;Huet, C.;Clairand, I
目的：本研究旨在表征TruView（TM）和ClearView（TM）两种新型凝胶剂量计（Modus Medical Devices Inc.）方法：在这项工作中，我们研究了这些辐射变色凝胶的关键剂量测定方面（剂量响应、能量和剂量率依赖性）和稳定性，这些辐射变色凝胶在初步工作中启动（Huet等人，2017; Colnot等人，2017）使用分光光度测量。结果：TruView（TM）和ClearView（TM）的线性剂量响应分别高达20戈伊和80戈伊，与光子束能量（4-18 MV）和剂量率（高达9.9戈伊/min）无关（Huet等，2017; Colnot等人，2017年）。ClearViewTM的响应被证明在辐照后一周内是稳定的，并且在批次内是均匀的，而TruViewTM呈现出不稳定但均匀的响应。光学CT扫描由于杂散光而产生误差，为了使用这些凝胶，需要校正杂散光; ClearView（TM）扫描特别需要重要的预防措施。校正后，与Vista（TM）扫描仪结合使用的凝胶显示出有希望的空间和剂量测定精度（剂量差异< 5%）。最后，TruView（TM）是可重复使用的，并提出了良好的重现性响应（最大3%的差异）和ClearView（TM）剂量计具有良好的空间稳定性（0.5%的差异后6天）。结论：这项研究提供了重要的知识，两个凝胶剂量计呈现有趣的剂量学特性。目前正在进行一项研究，以确定这些有希望的候选药物的临床剂量验证基准。
Purpose: This study aims at characterising the properties of TruView (TM) and ClearView (TM) two new gel dosimeters (Modus Medical Devices Inc.) and at studying the feasibility of relative dosimetry using these dosimeters and the Vista (TM) Optical CT scanner to accurately evaluate dose.Methods: In this work, we investigated key dosimetric aspects (dose response, energy and dose rate dependence) and stability of these radiochromic gels initiated in preliminary works (Huet et al., 2017; Colnot et al., 2017) using spectrophotometric measurements. Moreover, by mean of optical CT scanning (Vista (TM)), their performances to measure relative depth dose (PDD) and cross profiles were analysed.Results: TruView (TM) and ClearView (TM) present a linear dose response up to 20 Gy and up to 80 Gy respectively, independent of both photon beam energy (4-18 MV) and dose rate (up to 9.9 Gy/min) (Huet et al., 2017; Colnot et al., 2017). ClearView (TM) response proves to be stable for a week post-irradiation and uniform within the batch whereas TruView (TM) presents an unstable but uniform response. Optical CT scanning generates errors due to stray light that need to be corrected in order to use these gels; ClearView (TM) scanning particularly requires important precautions. After corrections, those gels used in combination with the Vista (TM) scanner show promising spatial and dosimetric precision (dose difference < 5%). Finally, TruView (TM) is reusable and presents excellent reproducible response (maximum 3% difference) and the ClearView (TM) dosimeter presents good spatial stability (0.5% difference after 6 days).Conclusion: This study provides important knowledge about two gel dosimeters presenting interesting dosimetric properties. A study is ongoing to benchmark those promising candidates for clinical dose verification.