Relationship between Habit of Cigarette Smoking and Airflow Limitation in Healthy Japanese Individuals: The Takahata Study
Relationship between Habit of Cigarette Smoking and Airflow Limitation in Healthy Japanese Individuals: The Takahata Study
复制标题
DOI：
10.2169/internalmedicine.49.3364
复制
发表时间：
2010-01-01
影响因子：
1.2
通讯作者：
Kubota, Isao
中科院分区：
文献类型：
--
作者：
Osaka, Daisuke;Shibata, Yoko;Kubota, Isao
Background Chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation. The prevalence of airflow limitation in Japan is 10.9% (16.4% of males and 5.0% of females). Cigarette smoking is well known as a major cause of COPD. However, few epidemiological studies have evaluated the effects of cigarette smoking on pulmonary function in healthy subjects.Methods Subjects aged 40 years or older (n=2,917), who had participated in a community-based annual health check in Takahata, Japan, from 2004 through 2005, were enrolled in the study. The smoking histories of these subjects were investigated using a self-reported questionnaire. Forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), and forced expiratory flow at 25-75% of FVC (FEF25-75) were measured by standard procedures using spirometric machines.Results There were 554 current smokers (18.6%) and 403 former smokers (13.8%). The prevalence of airflow limitation defined by FEV1/FVC
