Bacterial profile, antibiotic susceptibility pattern and associated risk factors of urinary tract infection among clinically suspected children attending at Felege-Hiwot comprehensive and specialized hospital, Northwest Ethiopia. A prospective study

Bacterial profile, antibiotic susceptibility pattern and associated risk factors of urinary tract infection among clinically suspected children attending at Felege-Hiwot comprehensive and specialized hospital, Northwest Ethiopia. A prospective study
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DOI:
10.1186/s12879-020-05402-y
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发表时间:
2020-09-16
影响因子:
3.7
通讯作者:
Belachew, Teshome
Belachew, Teshome
中科院分区:
医学3区
文献类型:
--
作者:
Fenta, Adugna;Dagnew, Mulat;Belachew, Teshome

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背景尿路感染是儿童最常见的细菌感染之一。了解尿路病原体的特点及其在特定环境下的抗菌药物敏感性模式可以为适当的病例管理提供证据。本研究旨在评估埃塞俄比亚西北部Felege-Hiwot综合专科医院临床疑似儿童尿路感染的细菌谱、抗菌药物敏感性及其相关因素。方法于2019年2 - 4月进行以医院为基础的横断面研究。采用了系统的抽样技术。将中游尿样接种于胱氨酸乳糖电解质缺乏培养基上,孵育24-48h。在Mac-Conkey和血琼脂上进行继代培养。对Muller-Hinton琼脂进行药敏试验。采用二元logistic回归模型分析因变量与自变量之间的关系。一个假定值
BackgroundUrinary tract infection is one of the most common bacterial infections in children. Understanding the characteristics of uropathogens and their antimicrobial susceptibility pattern in a particular setting can provide evidence for the appropriate management of cases. This study aimed to assess the bacterial profile of urinary tract infection, their antimicrobial susceptibility pattern and associated factors among clinically suspected children attending at Felege-Hiwot Comprehensive Specialized Hospital, Northwest Ethiopia.MethodsA hospital-based cross-sectional study was conducted from February-April, 2019. A systematic sampling technique was employed. A mid-stream urine sample was inoculated on cystine lactose electrolyte deficient media and incubated for 24-48h. Sub-culturing was done on Mac-Conkey and blood agar. Antimicrobial susceptibility test was done on Muller-Hinton agar. A binary logistic regression model was used to see the association between dependent and independent factors. A p-value