The relative rates of synthesis of DNA, sRNA and rRNA in the endodermal region and other parts of Xenopus laevis embryos.
The relative rates of synthesis of DNA, sRNA and rRNA in the endodermal region and other parts of Xenopus laevis embryos.
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非洲爪蟾胚胎内胚层区域和其他部分 DNA、sRNA 和 rRNA 合成的相对速率。
DOI：
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发表时间：
1968
期刊：
影响因子：
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通讯作者：
J. Gurdon
中科院分区：
文献类型：
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作者：
H. Woodland;J. Gurdon
在整个青蛙胚胎的发育过程中，主要类别核酸的合成起始和合成速率已被广泛研究（Brown，1965 年评论；Gurdon，1967 年 a）。这些信息很有趣，因为核酸是基因的直接产物，因此它们的合成速率提供了基因活性变化的直接测量。迄今为止，青蛙胚胎部分的核酸合成主要通过不区分不同类别 RNA 的方法进行分析（例如 Bachvarova & Davidson, 1966; Flickinger, Miyagi, Moser & Rollins, 1967）。由于胚胎由许多不同的细胞类型组成，因此了解在整个胚胎中观察到的核酸合成模式对于其各个区域，特别是对于一种分化细胞类型来说在多大程度上是真实的非常重要。
The onset and rates of synthesis of the major classes of nucleic acids have been extensively studied during the development of whole frog embryos (reviews by Brown, 1965; Gurdon, 1967 a ). Such information is of interest because nucleic acids are the immediate products of genes, and their rates of synthesis therefore provide a direct measure of changes in gene activity. To date nucleic acid synthesis in parts of frog embryos has been analysed mainly by methods which do not distinguish different classes of RNA (e.g. Bachvarova & Davidson, 1966; Flickinger, Miyagi, Moser & Rollins, 1967). Since embryos consist of many different cell types, it is important to know to what extent the pattern of nucleic acid synthesis observed in the whole embryo is true for its individual regions, and in particular for one differentiating cell type.