The role of autoantibody-producing plasma cells in immune thrombocytopenic purpura refractory to rituximab
The role of autoantibody-producing plasma cells in immune thrombocytopenic purpura refractory to rituximab
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DOI：
10.1002/ajh.20951
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发表时间：
2007-09-01
影响因子：
12.8
通讯作者：
Urabe, A.
中科院分区：
文献类型：
--
作者：
Kuwana, M.;Iki, S.;Urabe, A.
Rituximab is becoming popular as a treatment for immune thrombocytopenic purpura (ITP). We report here a patient with ITP, who initially responded to rituximab, but later became refractory. In this patient, the appearance of plasma cells producing anti-platelet autoantibodies is likely to be one of the mechanisms for rituximab resistance.
