Role of microRNAs in programmed cell death in renal diseases: A review.
Role of microRNAs in programmed cell death in renal diseases: A review.
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DOI：
10.1097/md.0000000000033453
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发表时间：
2023-04-14
期刊：
影响因子：
1.6
通讯作者：
中科院分区：
文献类型：
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作者：
MicroRNAs (miRNAs) regulate gene expression involving kidney morphogenesis and cell proliferation, apoptosis, differentiation, migration, invasion, immune evasion, and extracellular matrix remodeling. Programmed cell death (PCD) is mediated and regulated by specific genes and a wealth of miRNAs, which participate in various pathological processes. Dysregulation of miRNAs can disrupt renal development and induce the onset and progression of various renal diseases. An in-depth understanding of how miRNAs regulate renal development and diseases is indispensable to comprehending how they can be used in new diagnostic and therapeutic approaches. However, the mechanisms are still insufficiently investigated. Hence, we review the current roles of miRNA-related signaling pathways and recent advances in PCD research and aim to display the potential crosstalk between miRNAs and PCD. The prospects of miRNAs as novel biomarkers and therapeutic targets are also described, which might provide some novel ideas for further studies.
影响因子：
4
作者：
Lin S;Wang Y;Zhao Z;Wu W;Su Y;Zhang Z;Shen M;Wu P;Qian H;Guo X
通讯作者：
Guo X
影响因子：
5.6
作者：
Opazo-Ríos L;Tejera-Muñoz A;Soto Catalan M;Marchant V;Lavoz C;Mas Fontao S;Moreno JA;Fierro Fernandez M;Ramos R;Suarez-Alvarez B;López-Larrea C;Ruiz-Ortega M;Egido J;Rodrigues-Díez RR
通讯作者：
Rodrigues-Díez RR
miR-17-5p通过抑制PTEN和BIM途径减轻肾脏缺血再灌注损伤
影响因子：
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作者：
Ma M;Fu L;Jia Z;Zhong Q;Huang Z;Wang X;Fan Y;Lin T;Song T
通讯作者：
Song T