Accuracy evaluation in the measurement of a small change in the thickness of arterial walls and the measurement of elasticity of the human carotid artery
Accuracy evaluation in the measurement of a small change in the thickness of arterial walls and the measurement of elasticity of the human carotid artery
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DOI：
10.1143/jjap.37.3101
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发表时间：
1998-05-01
期刊：
影响因子：
--
通讯作者：
Koiwa, Y
中科院分区：
文献类型：
--
作者：
Hasegawa, H;Kanai, H;Koiwa, Y
动脉壁局部声学特性的评价对于动脉粥样硬化的早期诊断具有重要意义。为此，有必要将轴向的空间分辨率提高到几毫米，这对应于壁表面上黄斑病变的大小。我们提出了一种利用脉冲超声波测量皮肤表面动脉内膜和外膜上微小速度信号的方法。通过对内膜和外膜上的两个速度信号之间的差进行积分来获得动脉壁厚度的微小变化。根据厚度变化和动脉内压无创地评价动脉壁的弹性性质。在本文中，我们评估所提出的方法测量小位移的准确性。并应用此方法对50例患者和8例健康人的动脉壁弹性进行了评价。
For the diagnosis of the early stages of atherosclerosis, it is important to evaluate the local acoustic characteristics of the arterial wall. For this purpose, it is necessary to increase the spatial resolution in the axial direction to several millimeters, which corresponds to the size of the macular lesion on the surface of the wall. We have proposed a method for measuring small velocity signals on the intima and adventitia of the arterial wall from the skin surface using pulsive ultrasonic waves. The small change in thickness of the arterial wall is obtained by integrating the difference between the two velocity signals on the intima and adventitia. The elastic property of the arterial wall is noninvasively evaluated from the change in thickness and the arterial inner pressure. In this paper, we evaluate the accuracy of the proposed method for measuring the small displacement. Moreover, we applied this method to evaluate the elastic properly of the arterial wall of 50 patients and 8 healthy subjects.