Effectiveness of narrow band imaging in the detection of premalignant and malignant lesions of the larynx: Validation of a new endoscopic clinical classification
Effectiveness of narrow band imaging in the detection of premalignant and malignant lesions of the larynx: Validation of a new endoscopic clinical classification
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DOI：
10.1002/hed.23582
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发表时间：
2015-02-01
影响因子：
2.9
通讯作者：
Benazzo, Marco
中科院分区：
文献类型：
--
作者：
Bertino, Giulia;Cacciola, Salvatore;Benazzo, Marco
BackgroundThe目的是评估窄带成像（NBI）内镜在咽喉病变诊断中的价值，并证明一种新的基于NBI的血管模式分类的有效性。根据Ni分型将NBI表现分为5种类型，并与组织病理学报告进行比较。结果敏感性、特异性、准确性、阳性预测值（PPV）和阴性预测值（NPV）分别为97.4%、84.6%、92.7%、91.6%和95.1%。98%的组织学恶性病变对应于V型内镜模式，而84.8%的非肿瘤性病变对应于I型到IV型pattern. ConclusionNBI检测粘膜微血管变化的能力可以用于区分非恶性病变。国际公认的NBI-内镜分类可能有助于进一步定义该技术的诊断有效性。(c)2014 Wiley Periodicals，Inc.头颈部37：215-222，2015
BackgroundThe purpose of this study was to assess the value of narrow band imaging (NBI) endoscopy in the diagnosis of pharyngolaryngeal lesions and to demonstrate the validity of a new NBI-based classification of their vascular pattern.MethodsFrom 2009 to 2011, 248 patients with pharyngolaryngeal lesions underwent NBI-endoscopic evaluation. NBI findings were classified into 5 types according to the Ni classification and were compared with histopathological reports. Sensitivity, specificity, accuracy, and positive predictive value (PPV) and negative predictive value (NPV) were calculated.ResultsSensitivity, specificity, accuracy, PPV, and NPV were 97.4%, 84.6%, 92.7%, 91.6%, and 95.1%, respectively. Ninety-eight percent of histologically malignant lesions corresponded to type V endoscopic pattern, whereas 84.8% of the non-neoplastic lesions corresponded to a type I to IV pattern.ConclusionThe NBI ability to detect changes in the mucosal microvasculature can be useful for distinguishing nonmalignant from malignant lesions. An internationally accepted NBI-endoscopic classification may contribute to the further definition of the diagnostic validity of this technique. (c) 2014 Wiley Periodicals, Inc. Head Neck37: 215-222, 2015