STRUCTURES OF THE O-CHAINS FROM LIPOPOLYSACCHARIDES OF CAMPYLOBACTER-JEJUNI SEROTYPES O/23 AND O/36
STRUCTURES OF THE O-CHAINS FROM LIPOPOLYSACCHARIDES OF CAMPYLOBACTER-JEJUNI SEROTYPES O/23 AND O/36
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DOI：
10.1016/0008-6215(92)84003-b
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发表时间：
1992-07-02
影响因子：
3.1
通讯作者：
PANG, H
中科院分区：
文献类型：
--
作者：
ASPINALL, GO;MCDONALD, AG;PANG, H
空肠弯曲杆菌血清型 O : 23 和 O : 36 的脂多糖已被证明含有结构可变的 O 多糖链，具有四种密切相关类型的重复单元： --> 3)-beta-D-Glc p NAc-(1 --> 3)-alpha-D-Gal p-(1 --> 2)-6d-alpha-D-alt-Hep p-(1 -->, --> 3)-β-D-Glc p NAc-(1 --> 3)-alpha-D-Gal p-(1 --> 2)-6d-3-Me-alpha-D-alt-Hep p-(1 -->, --> 3)-beta-D-Glc p NAc-(1 --> 3)-alpha-D-Gal p-(1 --> 2)-D-甘油-alpha-D-alt-Hep p-(1 -->, and --> 3)-beta-D-Glc p NAc-(1 --> 3)-alpha-D-Gal p-(1 --> 2)-3-Me-D-glycero-alpha-D-alt-Hep p-(1 -->。结构方法包括 H-1- 和 C-13-NMR 光谱、甲基化键分析、甲基化聚糖的快速原子轰击质谱和选择性断裂通过Smith降解和N-脱乙酰化-亚硝酸脱氨基作用。
Lipopolysaccharides of C jejuni serotypes O : 23 and O : 36 have been shown to contain structurally variable O polysaccharide chains with repeating units of four closely-related types: --> 3)-beta-D-Glc p NAc-(1 --> 3)-alpha-D-Gal p-(1 --> 2)-6d-alpha-D-alt-Hep p-(1 -->, --> 3)-beta-D-Glc p NAc-(1 --> 3)-alpha-D-Gal p-(1 --> 2)-6d-3-Me-alpha-D-alt-Hep p-(1 -->, --> 3)-beta-D-Glc p NAc-(1 --> 3)-alpha-D-Gal p-(1 --> 2)-D-glycero-alpha-D-alt-Hep p-(1 -->, and --> 3)-beta-D-Glc p NAc-(1 --> 3)-alpha-D-Gal p-(1 --> 2)-3-Me-D-glycero-alpha-D-alt-Hep p-(1 -->.Structural methods included H-1- and C-13-NMR spectroscopy, methylation linkage analysis, fast atom bombardment mass spectrometry of methylated glycans, and selective fragmentations by the Smith degradation and N-deacetylation-nitrous acid deamination.