Beta-adrenergic receptor function in affective illness.
Beta-adrenergic receptor function in affective illness.
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β-肾上腺素能受体在情感疾病中发挥作用。
DOI：
10.1176/ajp.136.5.675
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发表时间：
1979
期刊：
影响因子：
--
通讯作者：
J. Davis
中科院分区：
文献类型：
--
作者：
G. Pandey;M. Dysken;D. Garver;J. Davis
In a study of beta-adrenergic receptor sensitivity, the authors determined the response of cyclic AMP synthesis to in vitro addition of norepinephrine (NE) and isoproterenol (IP) in leukocytes of patients with affective illness and schizophrenia and of normal controls. IP-stimulated increase in 3H-cyclic AMP synthesis in depressed patients was significantly lower than in normal subjects and schizophrenic patients. These results suggest that beta-adrenergic receptor sensitivity is reduced in depressive illness.
