Revision of breast cancer staging: the 6th edition of the TNM Classification.
Revision of breast cancer staging: the 6th edition of the TNM Classification.
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DOI：
10.1002/ssu.10021
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发表时间：
2003-01-01
期刊：
影响因子：
--
通讯作者：
Greene, Frederick L
中科院分区：
文献类型：
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作者：
Singletary, S Eva;Greene, Frederick L
由乳腺癌治疗领域的全国知名专家组成的乳房特别工作组负责根据已公布的证据和/或与广泛的临床共识一致的建议，对第6版的TNM分类提出补充和修改建议。对分期系统的增加是为了便于统一收集有关检测转移细胞的新技术的临床相关信息。这些补充包括区分微转移和分离的肿瘤细胞的定量标准，以及记录前哨淋巴结活检、免疫组织化学(IHC)染色和分子生物学技术使用的特定识别符。对先前分期系统的修订与受累腋窝淋巴结的数目以及腋窝外III级腋窝淋巴结的分类有关。
A Breast Task Force comprised of nationally known experts in the field of breast cancer treatment was charged with recommending additions and changes for the 6th edition of the TNM Classification that were based on published evidence and/or were consistent with widespread clinical consensus. Additions made to the staging system were designed to facilitate the uniform collection of clinically relevant information about new techniques for the detection of metastatic cells. These additions include quantitative criteria to distinguish micrometastases from isolated tumor cells, and specific identifiers to record the use of sentinel lymph node biopsy, immunohistochemical (IHC) staining, and molecular biology techniques. Revisions of the previous staging system are related to the number of affected axillary lymph nodes and to the classification of level III axillary lymph nodes and lymph nodes outside of the axilla.