Petri Net Based Model Validation in Systems Biology
Petri Net Based Model Validation in Systems Biology
复制标题
系统生物学中基于 Petri 网的模型验证
DOI:
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复制
发表时间:
2004
期刊:
影响因子:
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通讯作者:
I. Koch
中科院分区:
文献类型:
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作者:
M. Heiner;I. Koch
This paper describes the thriving application of Petri net theory for model validation of different types of molecular biological systems. After a short introduction into systems biology we demonstrate how to develop and validate qualitative models of biological pathways in a systematic manner using the well-established Petri net analysis technique of place and transition invariants. We discuss special properties, which are characteristic ones for biological pathways, and give three representative case studies, which we model and analyse in more detail. The examples used in this paper cover signal transduction pathways as well as metabolic pathways.
DOI:
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发表时间:
1991
期刊:
The New biologist
影响因子:
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作者:
Savageau,MA
通讯作者:
Savageau,MA