Vascular complications of pancreatitis: role of interventional therapy.
Vascular complications of pancreatitis: role of interventional therapy.
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DOI：
10.3348/kjr.2012.13.s1.s45
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发表时间：
2012-01
影响因子：
4.8
通讯作者：
Lopera JE
中科院分区：
文献类型：
--
作者：
Barge JU;Lopera JE
与胰腺炎相关的严重血管并发症可导致危及生命的出血，必须作为急诊处理，采用血管造影、内窥镜检查或手术等多学科方法。这些可能继发于直接血管损伤，导致内脏假性动脉瘤的形成，胃肠道病因如消化性溃疡病和胃食管静脉曲张，以及与胰腺手术相关的术后出血。在这篇综述文章中，我们讨论了胰腺血管并发症的病理生理机制、诊断方式和治疗，重点是微创介入治疗（如血管栓塞、血管内支架植入术和超声引导下经皮凝血酶注射）在其管理中的作用。
Major vascular complications related to pancreatitis can cause life-threatening hemorrhage and have to be dealt with as an emergency, utilizing a multidisciplinary approach of angiography, endoscopy or surgery. These may occur secondary to direct vascular injuries, which result in the formation of splanchnic pseudoaneurysms, gastrointestinal etiologies such as peptic ulcer disease and gastroesophageal varices, and post-operative bleeding related to pancreatic surgery. In this review article, we discuss the pathophysiologic mechanisms, diagnostic modalities, and treatment of pancreatic vascular complications, with a focus on the role of minimally-invasive interventional therapies such as angioembolization, endovascular stenting, and ultrasound-guided percutaneous thrombin injection in their management.