IS HYPERVISCOSITY A TREATABLE COMPONENT OF DIABETIC MICROCIRCULATORY DISEASE?
IS HYPERVISCOSITY A TREATABLE COMPONENT OF DIABETIC MICROCIRCULATORY DISEASE?
复制标题
高粘滞血症是糖尿病微循环疾病的可治疗部分吗？
DOI：
10.1016/s0140-6736(77)90724-3
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发表时间：
1977
期刊：
影响因子：
--
通讯作者：
Joan Slack
中科院分区：
文献类型：
--
作者：
A. Barnes;P. Locke;P. Scudder;T. Dormandy;J. A. Dormandy;Joan Slack
Blood viscosity at low shear-rates was significantly higher in sixty-four patients with longstanding diabetes than in sixty-one matched non-diabetic controls. This increase was most striking in patients with either proliferative retinopathy or nephropathy, although it was present to a lesser extent in diabetic patients with evidence of myocardial or peripheral ischæmia. Erythrocyte deformability was lower in the fourteen diabetic patients with the most extensive microangiopathy than in twenty-two diabetics with slight or no complications or in controls. Hyperviscosity and reduced erythrocyte deformability may well be important and potentially treatable factors in the ætiology or progression of microcirculatory disease in diabetes.
