The cortical visual area V6 in macaque and human brains
The cortical visual area V6 in macaque and human brains
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DOI：
10.1016/j.jphysparis.2009.05.012
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发表时间：
2009-01-01
影响因子：
--
通讯作者：
Galletti, Claudio
中科院分区：
文献类型：
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作者：
Fattori, Patrizia;Pitzalis, Sabrina;Galletti, Claudio
单细胞记录和神经解剖学技术在猴子的颞顶枕叶皮层中发现了视觉区域的马赛克。由于神经成像方法，这些区域中的几个也被映射到人类大脑中，并根据人类与非人类灵长类动物区域的视觉组织的同源性在人类中命名。我们最近发现了一个新的视网膜组织的皮层视觉区，我们称之为V6。V6区首先在猕猴中被描述，然后最近在人类中被描述。在这两种灵长类动物中，它位于大脑的内侧顶枕区。与其他纹外区一样，V6包含整个对侧半视野的视网膜定位图，但与其他纹外区不同，V6缺乏中央视野的强调。在猕猴中，V6区直接从VI和枕叶的其他纹外区域接收视觉信息，并将视觉信息发送到几个顶叶区域，所有这些区域都属于所谓的背侧视觉流。猕猴维斯的神经元对视觉刺激的运动方向非常敏感，并充当真实运动检测器。据报道，包括人类V6所在的皮质区域在内的皮质损伤的患者无法识别视觉刺激的运动方向，或者根据这些数据检测视觉运动本身。我们认为V6参与了视野中运动的“识别”。(C)2009爱思唯尔有限公司保留所有权利。
Single cell recording and neuro-anatomical techniques in the monkey have allowed to find a mosaic of visual areas in the temporo-parieto-occipital cortex. Thanks to neuroimaging methods, several of these areas have been mapped also in the human brain and named in humans based on homologies in their visuotopic organization with non-human primate areasWe have recently found a new, retinotopically-orgainized cortical visual area, that we have called V6. Area V6 was first described in the macaque monkey and then, recently, in the human. In both primates, it is located in the medial parieto-occipital region of the brain. Like the other extrastriate areas, V6 contains a retinotopic map of the entire contralateral hemifield, but unlike other extrastriate areas, V6 lacks an emphasis of the central visual field. In macaque, area V6 receives visual information directly from VI and from other extrastriate areas of the occipital lobe, and sends visual information to several parietal areas, all belonging to the so called dorsal visual stream. The neurons of macaque VIS are very sensitive to the direction of motion of visual stimuli and act as real-motion detectors. It has been reported that patients with cortical damages which include the cortical region where human V6 is located are unable to recognize the direction of motion of visual stimuli, or to detect the visual motion per se According to these data. we Suggest that V6 is involved in the 'recognition' of movement in the visual field. (C) 2009 Elsevier Ltd. All rights reserved.