Prophylactic lymph node dissection in clinical stage I cutaneous malignant melanoma: Results of surgical treatment in 1319 patients
Prophylactic lymph node dissection in clinical stage I cutaneous malignant melanoma: Results of surgical treatment in 1319 patients
复制标题
临床 I 期皮肤恶性黑色素瘤的预防性淋巴结清扫术：1319 例患者的手术治疗结果
作者：
G. Milton;H. Shaw;W. McCarthy;L. Pearson;C. Balch;S. Soong
一项回顾性研究对 1319 名临床上无疾病的皮肤原发性恶性黑色素瘤和区域淋巴结患者进行了回顾性研究，其首次明确的手术治疗是（a）原发性病变广泛切除（WE）或（b）原发性病变广泛切除加预防性淋巴结清扫（PLND）。根据多因素分析显示的三个主要预后因素对患者进行分层：患者性别、解剖部位和原发病变的厚度。
A retrospective study was made of 1319 patients with cutaneous primary malignant melanoma and regional lymph nodes clinically free of disease, whose first definitive surgical treatment was either (a) wide excision of the primary lesion (WE) or (b) wide excision of the primary lesion plus a prophylactic lymph node dissection (PLND). Patients were stratified according to three dominant prognostic factors, as revealed by multifactorial analyses: sex of patient, the anatomical site and thickness of the primary lesion.