RELATIVE PROPORTIONS OF HEMOPHILUS SPECIES IN THE THROAT OF HEALTHY-CHILDREN AND ADULTS

RELATIVE PROPORTIONS OF HEMOPHILUS SPECIES IN THE THROAT OF HEALTHY-CHILDREN AND ADULTS
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DOI:
10.1007/bf02014895
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发表时间:
1984-01-01
影响因子:
4.5
通讯作者:
KILIAN, M
KILIAN, M
中科院分区:
医学3区
文献类型:
--
作者:
KUKLINSKA, D;KILIAN, M

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为了确定咽部嗜血杆菌属的正常比例,使用选择性和非选择性培养基对10名健康儿童和10名健康成人的咽部中的物种进行定性和定量作图。嗜血杆菌生物体存在于所有样品中,包括占总可栽培植物群的0.6-36.9%。H.副流感病毒是正常植物群的成员,占咽部嗜血杆菌生物体的74%。H. segnis和H. 嗜热副螨在成虫中的发生频率较高;溶血性链球菌仅在1份样品中存在。非包囊H. 80%的儿童体内存在流感病毒株,通常具有多种生物型,但平均仅占总植物群的1.8%。其数量随年龄增长而减少,40%的成年人携带H。流感,但只有一个单一的生物型,占总植物群的一小部分(平均0.15%)。这些发现表明,宿主机制可以影响H比例的变化。流感病毒株在宿主体内定植。
To determine normal proportions of pharyngeal Haemophilus spp., qualitative and quantitative mapping of the species in the pharynx of 10 healthy children and 10 healthy adults was carried out using a selective and nonselective medium. Haemophilus organisms were present in all samples, comprising .apprx. 10% of the total cultivable flora (range 0.6-36.9%). H. parainfluenzae was a member of the normal flora throughout life, constituting 74% of pharyngeal Haemophilus organisms. H. segnis and H. paraphrophilus occurred more frequently in samples from adults; H. haemolyticus was present in only 1 sample. Non-encapsulated H. influenzae strains, usually of multiple biotypes, were present in 80% of the children but accounted for a mean of only 1.8% of the total flora. Their number decreased with increasing age; 40% of the adults harbored H. influenzae but only of a single biotype which constituted a minor proportion of the total flora (mean 0.15%). These findings suggest that host mechanisms can influence changes in the proportions of H. influenzae strains colonizing the host.