RELATIVE PROPORTIONS OF HEMOPHILUS SPECIES IN THE THROAT OF HEALTHY-CHILDREN AND ADULTS
RELATIVE PROPORTIONS OF HEMOPHILUS SPECIES IN THE THROAT OF HEALTHY-CHILDREN AND ADULTS
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DOI:
10.1007/bf02014895
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发表时间:
1984-01-01
影响因子:
4.5
通讯作者:
KILIAN, M
中科院分区:
文献类型:
--
作者:
KUKLINSKA, D;KILIAN, M
To determine normal proportions of pharyngeal Haemophilus spp., qualitative and quantitative mapping of the species in the pharynx of 10 healthy children and 10 healthy adults was carried out using a selective and nonselective medium. Haemophilus organisms were present in all samples, comprising .apprx. 10% of the total cultivable flora (range 0.6-36.9%). H. parainfluenzae was a member of the normal flora throughout life, constituting 74% of pharyngeal Haemophilus organisms. H. segnis and H. paraphrophilus occurred more frequently in samples from adults; H. haemolyticus was present in only 1 sample. Non-encapsulated H. influenzae strains, usually of multiple biotypes, were present in 80% of the children but accounted for a mean of only 1.8% of the total flora. Their number decreased with increasing age; 40% of the adults harbored H. influenzae but only of a single biotype which constituted a minor proportion of the total flora (mean 0.15%). These findings suggest that host mechanisms can influence changes in the proportions of H. influenzae strains colonizing the host.