LESSON OF THE WEEK - RENAL-INSUFFICIENCY WITH COMBINATIONS OF ANGIOTENSIN CONVERTING ENZYME-INHIBITORS AND DIURETICS
LESSON OF THE WEEK - RENAL-INSUFFICIENCY WITH COMBINATIONS OF ANGIOTENSIN CONVERTING ENZYME-INHIBITORS AND DIURETICS
复制标题
DOI：
10.1136/bmj.288.6420.844
复制
发表时间：
1984-01-01
影响因子：
--
通讯作者：
KINCAIDSMITH, P
中科院分区：
文献类型：
--
作者：
MURPHY, BF;WHITWORTH, JA;KINCAIDSMITH, P
双侧肾动脉狭窄的高血压患者使用血管紧张素转换酶抑制剂与可逆性肾功能损害相关。2在血管紧张素转换酶抑制剂中加入利尿剂之前，肾功能可能不会恶化，并且在停用利尿剂后可能会逆转。2我们报告了一名高血压肾硬化患者在联合使用利尿剂和两种不同的血管紧张素转换酶抑制剂治疗后发生的两次肾损害。该病例的额外关注点在于，尽管患者患有重度小肾血管疾病，但不存在主要肾动脉狭窄。
The use of angiotensin converting enzyme inhibitors in hypertensive patients with bilateral renal artery stenosis is associated with reversible impairment of renal function.'2 Deterioration in renal function may not occur until diuretics are added to the angiotensin converting enzyme inhibitors and may reverse after the diuretics are discontinued. 2We report two episodes of renal impairment after treatment with combinations of diuretic and two different angiotensin converting enzyme inhibitors in a patient with hypertensive nephrosclerosis. This case is of added interest in that, though the patient had severe small renal vessel disease, major renal artery stenosis was not present.